The GnRH Neuron and its Control

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Allan E. Herbison Tony M. Plant (University of Pittsburgh School of Medicine, USA)

The GnRH Neuron and its Control

Allan E. Herbison, Tony M. Plant (University of Pittsburgh School of Medicine, USA)

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English

Wiley-Blackwell
27 April 2018

Neurosciences; Animal physiology

Series: Wiley-INF Masterclass in Neuroendocrinology Series

The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release.

The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology.

This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Edited by: Allan E. Herbison, Tony M. Plant (University of Pittsburgh School of Medicine, USA)
Imprint: Wiley-Blackwell
Country of Publication: United Kingdom
Dimensions: Height: 244mm, Width: 165mm, Spine: 28mm
Weight: 1.066kg
ISBN: 9781119233244
ISBN 10: 1119233240
Series: Wiley-INF Masterclass in Neuroendocrinology Series
Pages: 536
Publication Date: 27 April 2018
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Editors: Allan E. Herbison, University of Otago, New Zealand. Tony M. Plant, University of Pittsburgh, USA.