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The Neurobiology of Cocaine Addiction: From Bench to Bedside

Herman Joseph Regina Quattrochi Barry Stimmel



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Routledge Member of the Taylor and Francis Group
18 March 1997
Regional physiology; Pharmacology; Human biology
With the use of crack on the rise in American cities, there is more need than ever to understand the biological, environmental, and social factors behind cocaine addiction, as well as the pharmacological properties of cocaine that make it such an addictive drug. The Neurobiology of Cocaine Addiction helps clinicians and researchers analyze research findings and their relevance to the clinical treatment of cocaine dependency. To do this, it looks at the whole spectrum of cocaine use, from trends in cocaine-involved deaths, hospital emergencies, arrests, and treatment admissions to the specific impact the drug has on brain function. The book reports on important findings from positron emission tomography (PET) and a binge pattern cocaine administration mode. This will enable you to improve your understanding of how cocaine alters the pleasure/reward system of the brain and creates new instinctual needs that displace the inherent instinctual needs of hunger and sex.

By reading The Neurobiology of Cocaine Addiction, you will sharpen your knowledge of the basic actions of cocaine, the factors related to daily cocaine use, the neurobiological basis of addictive diseases, and drug-induced alterations in normal physiology. You will also learn about:

the coexistence of cocaine and heroin addiction cocaine's disruption of the endogenous opioid system QEEG and how it can play a potentially useful role in drug development and planning hypotheses of sensitization in the pathophysiology of cocaine dependence factors that predict daily cocaine use among patients in a methadone maintenance program abnormalities in brain function that persist for up to six months after last cocaine use patterns of cocaine use the importance of prospective data analysis and the limitations of a self-selective study groupClinicians, researchers, psychiatrists, and other professionals in chemical dependency and narcotics rehabilitation will turn the last page of The Neurobiology of Cocaine Addiction with a better understanding of cocaine's addictive qualities and the characteristics of the individuals who become addicted to it. You will see what headway has been made in research at some of the nation's top laboratories, but you will also see what remains to be done. Hopefully, you will find where you can make a contribution either at the practical level, the research level, or both.
By:   Herman Joseph, Regina Quattrochi
Edited by:   Barry Stimmel
Imprint:   Routledge Member of the Taylor and Francis Group
Country of Publication:   United States
Dimensions:   Height: 229mm,  Width: 152mm,  Spine: 12mm
Weight:   408g
ISBN:   9780789000316
ISBN 10:   0789000318
Pages:   148
Publication Date:   18 March 1997
Audience:   College/higher education ,  General/trade ,  Professional and scholarly ,  Further / Higher Education ,  ELT Advanced
Format:   Hardback
Publisher's Status:   Active
Contents Editorial: Basic Science, Epidemiology, Clinical Practice, and Philanthropy Cocaine Trends and Other Drug Trends in New York City, 1986-1994 Daily Cocaine Use Patterns: Effects of Contextual and Psychological Variables Neurometric QEEG Studies of Crack Cocaine Dependence and Treatment Outcome Cocaine Addiction: Hypothesis Derived from Imaging Studies with PET Cocaine, Dopamine, and the Endogenous Opioid System Pattern of Cocaine Use in Methadone-Maintained Individuals Applying for Research Studies Selective Guide to Current Reference Sources on Topics Discussed in This Issue Index Reference Notes Included

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