The Neurobiology of Cocaine Addiction

From Bench to Bedside

Herman Joseph, Regina Quattrochi, Barry Stimmel

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English

Routledge
19 March 1997

Regional physiology; Pharmacology; Human biology; Popular medicine & health

With the use of crack on the rise in American cities, there is more need than ever to understand the biological, environmental, and social factors behind cocaine addiction, as well as the pharmacological properties of cocaine that make it such an addictive drug. The Neurobiology of Cocaine Addiction helps clinicians and researchers analyze research findings and their relevance to the clinical treatment of cocaine dependency. To do this, it looks at the whole spectrum of cocaine use, from trends in cocaine-involved deaths, hospital emergencies, arrests, and treatment admissions to the specific impact the drug has on brain function. The book reports on important findings from positron emission tomography (PET) and a “binge” pattern cocaine administration mode. This will enable you to improve your understanding of how cocaine alters the pleasure/reward system of the brain and creates new instinctual needs that displace the inherent instinctual needs of hunger and sex.

By reading The Neurobiology of Cocaine Addiction, you will sharpen your knowledge of the basic actions of cocaine, the factors related to daily cocaine use, the neurobiological basis of addictive diseases, and drug-induced alterations in normal physiology. You will also learn about:

the coexistence of cocaine and heroin addiction

cocaine’s disruption of the endogenous opioid system

QEEG and how it can play a potentially useful role in drug development and planning

hypotheses of sensitization in the pathophysiology of cocaine dependence

factors that predict daily cocaine use among patients in a methadone maintenance program

abnormalities in brain function that persist for up to six months after last cocaine use

patterns of cocaine use

the importance of prospective data analysis and the limitations of a self-selective study groupClinicians, researchers, psychiatrists, and other professionals in chemical dependency and narcotics rehabilitation will turn the last page of The Neurobiology of Cocaine Addiction with a better understanding of cocaine’s addictive qualities and the characteristics of the individuals who become addicted to it. You will see what headway has been made in research at some of the nation’s top laboratories, but you will also see what remains to be done. Hopefully, you will find where you can make a contribution either at the practical level, the research level, or both.

By: Herman Joseph, Regina Quattrochi
Edited by: Barry Stimmel
Imprint: Routledge
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm, Spine: 11mm
Weight: 226g
ISBN: 9780789003003
ISBN 10: 0789003007
Pages: 146
Publication Date: 19 March 1997
Audience: College/higher education , General/trade , Professional and scholarly , Further / Higher Education , ELT Advanced
Format: Paperback
Publisher's Status: Active

Herman Joseph, Barry Stimmel