Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery

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Dipankar Chattopadhyay (Professor, Department of Polymer Science and Technology, University Colleges of Science and Technology, University of Calcutta, India) Jonathan Tersur Orasugh (Dept. of Polymer Science & Technology, University Colleges of Science & Technology, University of Calcutta)

Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery

Dipankar Chattopadhyay (Professor, Department of Polymer Science and Technology, University Colleges of Science and Technology, University of Calcutta, India), Jonathan Tersur Orasugh (Dept. of Polymer Science & Technology, University Colleges of Science & Technology, University of Calcutta), Anjan Adhikari, MBBS, MD (Professor & Head, Department of Pharmacology, Coochbehar Government Medical College & Hospital)

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English

Woodhead Publishing
20 May 2024

Biomedical engineering; Biotechnology; Materials science

Series: Woodhead Publishing Series in Biomaterials

This book covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels; the properties, characterization, chemistry, and fabrication of these hydrogels is detailed, helping the reader to select the most appropriate material and design for the desired application. The book goes on to review applications in ophthalmic drug delivery, covering in vitro and in vivo models, animal models, preclinical testing, patents and more. Stimuli-responsive Hydrogels for Ophthalmic Drug Delivery is a must-have reference for researchers and academics in the fields of materials science, biomaterials, pharmacology and polymer science, with an interest in clinical aspects of hydrogel design and application.

By: Dipankar Chattopadhyay (Professor Department of Polymer Science and Technology University Colleges of Science and Technology University of Calcutta India), Jonathan Tersur Orasugh (Dept. of Polymer Science & Technology, University Colleges of Science & Technology, University of Calcutta), Anjan Adhikari, MBBS, MD (Professor & Head, Department of Pharmacology, Coochbehar Government Medical College & Hospital)
Imprint: Woodhead Publishing
Country of Publication: United States
Dimensions: Height: 229mm, Width: 151mm,
ISBN: 9780323991568
ISBN 10: 0323991564
Series: Woodhead Publishing Series in Biomaterials
Pages: 500
Publication Date: 20 May 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Forthcoming

Part I: Properties and Preparation 1. Introduction to polymeric in-situ forming hydrogels 2. Biopolymers for in-situ forming hydrogels: synthesis, characterization, and toxicity 3. Chemistry and applications of biopolymer stimuli-responsive in-situ gels 4. Design, engineering, and fabrication of biopolymer in-situ forming hydrogels 5. Process optimization for design and fabrication of biopolymer stimuli-responsive hydrogels 6. Properties of biopolymeric in-situ hydrogels 7. Swelling and drug release kinetics of biopolymer in-situ forming hydrogels 8. Structural and load-bearing characteristics of biopolymer in-situ forming hydrogels 9. Functionalization of in-situ forming biopolymer hydrogels Part II: Applications in Ophthalmic Drug Delivery 10. Eye anatomy, physiology, and ocular barriers 11. In vitro and in vivo models in ophthalmic drug delivery 12. Formulation and ocular drug delivery routes 13. Clinical indications of stimuli-responsive hydrogels in ophthalmic drug delivery 14. Natural and synthetic materials for stimuli-responsive hydrogels in ophthalmic drug delivery 15. Characteristics and kinetics of in-situ forming hydrogels in ophthalmic drug delivery 16. Cell-laden stimuli-responsive hydrogels in ophthalmic drug delivery 17. Animal models and preclinical tests for evaluation of stimuli-responsive hydrogels in ophthalmic drug delivery 18. Biopolymer-based in-situ forming hydrogels: from laboratory to practical application 19. Commercially available stimuli-responsive hydrogels for ophthalmic drug delivery 20. Advantages and challenges of biopolymer in-situ hydrogels for ophthalmic drug delivery 21. Patents for biopolymer in-situ hydrogels for ophthalmic drug delivery

Prof. Dipankar Chattopadhyay is an eminent professor currently working in the Department of Polymer Science & Technology, University of Calcutta, India since 2006 and also a former HOD. Earlier, he worked as a lecturer at the Vidhyasagar University and Shahid Bhagat Singh College, Punjab, India. He obtained his B.Tech in Plastics & Rubber Technology from University of Calcutta, India and M.Tech in Polymer Science and Engineering, IIT, New Delhi with Ph.D. (Polymer Science) from the IACS, India. He is an experienced research professional with expertise in polymers nanocomposites, biomaterials, and nanomaterials. He has ~22 years of research experience with completed 10 research project and collaborative projects with industries. He is an active reviewer for various Journals and supervised >20 scholars and five post-doctorate students. He has 127 publications and has 3 patents. He is an Executive Member in the Society for Polymer Science, India; MRSI, Calcutta Chapter and many more. Dr. Jonathan Tersur Orasugh is currently a research associate/teaching assistant at Ministry of Textiles, Inspire Faculty, Dept. of Polymer Science & Technology, University of Calcutta. He has Ph.D. (Nanoscience and Nanotechnology) and M.Tech (Technical Textiles: Fibre Technology) from University of Calcutta, Kolkata, and B.Tech. (Textile Technology) from Kaduna Polytechnic, Kaduna, Nigeria. He has published more than 10 research articles in diverse international journals along with more than 5 book chapters with publishers of high repute. He is an active editor with five international journals and a reviewer with different international journals. He has more than 6yrs of research experience in the field of polymer composites and nanocomposites, synthesis, and surface treatment of nanomaterials along with their potential applications. He is also an executive board member and research head at EL-YOTEK NIG. LTD. He is also a research consultant with AMER-SIL KETEX PVT LTD., India. Dr. Anjan Adhikari is a practicing medical doctor and Head of Pharmacology Department at the Coochbehar Govt. Medical College & Hospital. Dr A. Adhikari is a member of several medical and pharmacological committees, including the Pharmacovigilance and Institutional Ethics committees at Coochbehar Government Medical College & Hospital; he is also a member of the Pharmacovigilance Programme of India (PvPI), Indian Pharmacopeia Commission, Govt. of India, Gaziabad, India and of the Subject Expert Committee (SEO), Central Drug Standard Control Organization (CDSCO), Govt. of India, New Delhi. Dr. Adhikari is a part of the Indian Council of Medical Research (ICMR), New Delhi. Dr. A. Adhikari is the Editor of the Rational Drug Bulletin, India and a reviewer for the Indian Journal of Pharmacology, as well as a number of National and International Journals.