Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Franck Mauvais-Jarvis

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English

Springer International Publishing AG
09 January 2018

Medical research; Physiology; Endocrinology; Urology & urogenital medicine; Biochemistry

Series: Advances in Experimental Medicine and Biology

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence boththe development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Edited by: Franck Mauvais-Jarvis
Imprint: Springer International Publishing AG
Country of Publication: Switzerland
Edition: 2017 ed.
Volume: 1043
Dimensions: Height: 235mm, Width: 155mm,
Weight: 1.434kg
ISBN: 9783319701776
ISBN 10: 3319701770
Series: Advances in Experimental Medicine and Biology
Pages: 627
Publication Date: 09 January 2018
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Franck Mauvais-Jarvis, MD, PhD, is Director of the Diabetes Discovery Research & Gender Medicine Laboratory, and Professor of Medicine, Section of Endocrinology and Metabolism, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.