Protein Design and Structure

1. Algorithms for protein design Sekhar Talluri 2. Computational prediction of protein functional sites—Applications in biotechnology and biomedicine Florencio Pazos 3. Structure and chemistry of enzymatic active sites that play a role in the switch and conformation mechanism Chandrabose Selvaraj, Ondipilliraja Rudhra, Abdulaziz S. Alothaim, Mustfa Alkhanani, and Sanjeev Kumar Singh 4. Accelerating therapeutic protein design Mohammad ElGamacy 5. Aromatic interactions directing peptide nano-assembly Sajitha Sasidharan and Vibin Ramakrishnan 6. Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families Jose C. Martinez, Francisco Castillo, Javier Ruiz-Sanz, Javier Murciano-Calles, Ana Camara-Artigas, and Irene Luque 7. The structural basis of histone modifying enzyme specificity and promiscuity: Implications for metabolic regulation and drug design Tim J. Kamerzell, Brittney Mikell, Lei Chen, Harold Elias, Buddhadeb Dawn, Calum MacRae, and C. Russell Middaugh 8. Designing synthetic transcription factors: A structural perspective Aparna Boral, Madhurima Khamaru, and Devrani Mitra 9. Recent advances in structural studies of 14-3-3 protein complexes Nikolai N. Sluchanko 10. Immunosafe(r)-by-design nanoparticles: Molecular targets and cell signaling pathways in a next-generation model proxy for humans Annalisa Pinsino and Maria Di Bernardo 11. Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach S. Udhaya Kumar, Balu Kamaraj, Rinku Polachirakkal Varghese, V. Anu Preethi, R. Bithia, and C. George Priya Doss 12. Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface D. Thirumal Kumar, S. Udhaya Kumar, Nikita Jain, Baviri Sowmya, Kamakshi Balsekar, R. Siva, Balu Kamaraj, Mariem Sidenna, C. George Priya Doss, and Hatem Zayed 13. Evolutionary aspect of Miltefosine transporter proteins in Leishmania major Ritika Kabra and Shailza Singh