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English
Academic Press Inc
25 July 2025
Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.

Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.
Edited by:   , , , , ,
Imprint:   Academic Press Inc
Country of Publication:   United States [Currently unable to ship to USA: see Shipping Info]
Dimensions:   Height: 235mm,  Width: 191mm, 
Weight:   450g
ISBN:   9780443300042
ISBN 10:   0443300046
Pages:   684
Publication Date:  
Audience:   Professional and scholarly ,  College/higher education ,  Undergraduate ,  Further / Higher Education
Format:   Paperback
Publisher's Status:   Active
Part I: PATHOPHYSIOLOGY AND NEUROBIOLOGY 1. Understanding Sleep in Narcolepsy: Sleep Physiology and Neurobiology 2. Pathophysiology of Narcolepsy: Genetics and Immune System 3. The Hypocretin/Orexin, Histamine, and Other Neurotransmitters in Narcolepsy: An Animal Model Perspective 4. The Gut-Brain Axis in Narcolepsy: Emerging Research on Microbiota, Diet, and Sleep Part II: CLINICAL ASPECTS 5. Types of Narcolepsy and Their Symptoms: Differential Diagnosis and Misdiagnosis 6. Delayed Diagnosis of Narcolepsy: Causes and Implications 7. Diagnostic Tools for Narcolepsy: Sleep Studies, MSLT, and More 8. Narcolepsy in Children and Adolescents: Diagnosis, Management, and Challenges 9. Narcolepsy and Pregnancy: Risks and Strategies for Management 10. Aging with Narcolepsy: Understanding the Unique Challenges for Older Adults 11. Medical Co-morbidities of Narcolepsy 12. More Than Just Narcolepsy: The Importance of Recognizing Concurrent Sleep Disorders 13. Narcolepsy and Circadian Rhythm Disorders: Diagnosis and Management 14. The Hidden Link Between Narcolepsy and Autonomic Dysfunction: A Closer Look 15. Narcolepsy and Metabolic Rate: What Do We Know? 16. Narcolepsy and Driving: Safety Issues and Regulations 17. The Natural History of Narcolepsy: Lessons from Longitudinal Studies 18. Narcolepsy and COVID-19: Implications for Diagnosis, Treatment, and Management 19. Neuroimaging in Narcolepsy: Advances in Understanding Pathophysiology and Diagnosis 20. The Distinctive Characteristics of REM Sleep and Dreams in Narcolepsy Part III: BEHAVIORAL AND PSYCHOSOCIAL CONSIDERATIONS 21. The Hidden Burden of Narcolepsy: Anxiety and Depression Among Patients 22. Understanding Psychosis and Behavioral Abnormalities in Narcolepsy Patients 23. Narcolepsy and Cognitive Impairment: Causes and Management 24. Coping with Narcolepsy: Lifestyle Changes, Academic Performance Challenges, and Employment Strategies for Success 25. Narcolepsy and Relationships: Navigating Intimacy, Family, and Social Life 26. Narcolepsy and Advocacy: Awareness, Education, and Community Building 27. Voices of Narcolepsy: Patient Perspectives on Living with a Chronic Condition 28. The Complexities of Medico-legal Assessment of Disability in Narcolepsy Part IV: SPECIFIC MANAGEMENT 29. Current Pharmacological Treatments for Narcolepsy 30. Exploring the Potential of Cognitive Behavioral Therapy as an Adjunct to Medication in Narcolepsy Management 31. Emerging Therapies for Narcolepsy: Immunotherapy, Gene Therapy, and Beyond 32. Exploring the Role of Biomarkers and Epigenetics in Narcolepsy: Implications for Diagnosis and Treatment 33. The Future of Narcolepsy Treatment: What Role Will Artificial Intelligence Play? 34. Narcolepsy and Chronic Pain: Implications and Management 35. Navigating the Economic Costs of Narcolepsy in Managed Care.

Ahmed S. BaHammam is a tenured Professor of Pulmonary and Sleep Medicine at King Saud University, Riyadh, Saudi Arabia. He has published over 450 peer-reviewed articles and book chapters, and authored or edited seven books in the fields of sleep medicine and respiratory disorders. Professor BaHammam is editor-in-chief of Nature and Science of Sleep and serves on the editorial board of several sleep medicine journals. He is the President-Elect of the Asian Society of Sleep Medicine. His research spans topics such as narcolepsy, hypersomnia, obesity hypoventilation syndrome, and the effects of intermittent fasting and mealtime on sleep and circadian rhythms. With more than three decades of dedicated experience in sleep medicine, Professor BaHammam has made lasting contributions to the understanding, diagnosis, and management of narcolepsy and other central hypersomnolence disorders. He is has received the King Saud University Lifetime Achievement Award for his contributions to sleep medicine research. Professor BaHammam also holds leadership roles as Executive Director of Academic Affairs at King Saud University Medical City and Director of both the Prince Naif Health Research Center and the University Sleep Research Center Dr. Amir Sharafkhaneh is a Professor of Medicine (tenured) at Baylor College of Medicine and a leading authority in sleep medicine. He completed his medical degree at Tehran University of Medical Sciences, followed by an internal medicine residency at Long Island College Hospital and a fellowship in Pulmonary, Critical Care, and Sleep Medicine at Baylor College of Medicine, where he also earned a PhD in medical research. With over 25 years of clinical and academic experience, Dr. Sharafkhaneh has authored numerous peer-reviewed publications and book chapters in the fields of pulmonary and sleep medicine. He founded the first accredited sleep medicine fellowship program in Texas and has since trained more than 100 sleep specialists. His work has been supported by multiple federal grants, including initiatives to develop telemedicine programs that expand access to sleep care in underserved areas. Dr. Sharafkhaneh currently co- chairs the VA clinical practice guideline committees for obstructive sleep apnea, insomnia, asthma, and COPD. His research team applies artificial intelligence and advanced data analytics to large-scale electronic health record data to advance the understanding and treatment of sleep and respiratory disorders. He also co-leads .the AI Interest Group of the World Sleep Society S.R. Pandi-Perumal, MSc., is the President and Chief Executive Officer of Somnogen Canada Inc., a Canadian corporation. Pandi is popular among the sleep community. He is a world- acclaimed sleep researcher and has authored over 300 publications and has edited over 25 high-profile academic volumes dealing with various sleep-related topics. His name is also on the list of the top 2% of scientists in the world, compiled by Stanford University, Elsevier, and SciTech Strategies. Drawn to the benefits and significance of the sleep cycle, his personal and professional careers have been involved in advocating/achieving a good night’s slumber. Further details about the editor can be viewed at https:// pandi-perumal.blogspot.com; https://scholar.google.com/citations?hl=en&user=MO90ZXkAAAAJ

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