Mitochondrial Disorders Caused by Nuclear Genes

Lee-Jun C. Wong

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English

Springer-Verlag New York Inc.
15 October 2014

Medical research; Medical genetics; Cytopathology

Summary
Details

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes. Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.

Edited by: Lee-Jun C. Wong
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States [Currently unable to ship to USA: see Shipping Info]
Edition: 2013 ed.
Dimensions: Height: 235mm, Width: 155mm, Spine: 20mm
Weight: 5.796kg
ISBN: 9781489992413
ISBN 10: 1489992413
Pages: 372
Publication Date: 15 October 2014
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active