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English
Academic Press Inc
13 February 2026
Microglial Aging: Basic, Translational and Clinical Advances
Edited by:  
Imprint:   Academic Press Inc
Country of Publication:   United States
Dimensions:   Height: 235mm,  Width: 191mm, 
Weight:   450g
ISBN:   9780443273407
ISBN 10:   0443273405
Pages:   382
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Section 1. Introduction to microglial aging and its involvement in neurodegenerative diseases 1. The microglial aging process at cellular and molecular levels across its different layers of complexity 2. Involvement of microglial aging in neurodegenerative diseases: a focus on Alzheimer’s disease 3. Involvement of microglial aging in neurodegenerative diseases: a focus on Parkinson’s disease 4. Involvement of microglial aging in neurodegenerative diseases: a focus on multiple sclerosis 5. Involvement of microglial aging in neurodegenerative diseases: a focus on amyotrophic lateral sclerosis 6. Involvement of microglial aging in neurodegenerative diseases: a focus on vascular cognitive impairment and dementia Section 2. Outcomes of the lifestyle on microglial aging and neurodegenerative diseases along the aging trajectory 7. Diet and the gut-brain axis 8. Sleep disturbances 9. Psychological stress 10. Bacterial and viral infections 11. Physical activity 12. Substance use Section 3. Emerging treatment strategies to rejuvenate microglia in aging and neurodegenerative diseases 13. Ketogenic diets and supplements 14. Senolytic drugs 15. Cannabinoids 16. Psychedelics 17. Plasmalogens 18. Multi-modal lifestyle interventions

Dr. Marie-Ève Tremblay is a Full Professor at the School of Medical Sciences, University of Victoria, British Columbia, Canada. She was awarded a Tier II Canada Research Chair in Neurobiology of Aging and Cognition until 2025. Dr. Tremblay is an internationally recognized leader in microglial research. Her career goal is to become a world leader in the development of innovative therapies normalizing microglial functions upon exposure to various environmental risk factors for disease throughout life. She has been invited to present her work over 143 times, at seminars, lectures at symposia, specialized courses, and other meetings. She has 182 publications cited 11,854 times, corresponding to an h-index of 50 and i10-index of 116 (Google Scholar). She was also named a Clarivate Highly Cited Researcher, being among the top 1% across fields in 2021 and 2022 and is ranked 4th world microglial expert by ExpertScape.

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