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Histophilus somni

Biology, Molecular Basis of Pathogenesis, and Host Immunity

Thomas J. Inzana

$251.95   $201.58

Hardback

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English
Springer International Publishing AG
19 April 2016
This volume reviews the current understanding of the taxonomy, disease syndromes, genetics, biology, and pathogenic factors of Histophilus somni, as well as the host immune response to this pathogen. H. somni is one of the most important bacterial pathogens in cattle and other ruminants, and its virulence factors are highly conserved with Haemophilus influenzae and other members of the Pasteurellaceae. H. somni has been recognized as a major cause of thrombotic meningoencephalitis, respiratory disease syndromes, myocarditis, reproductive disease syndromes, polyarthritis, mastitis, ocular disease, and septicemia. The only known habitats of H. somni are the mucosal surfaces of ruminants, making this bacterium an opportunistic pathogen. Although it is capable of causing inflammation at systemic sites and is toxic to epithelial and phagocytic cells, the bacterium’s wide array of virulence factors act primarily as a defense against, or to escaperecognition from, host innate and adaptive immunity.
Edited by:  
Imprint:   Springer International Publishing AG
Country of Publication:   Switzerland
Edition:   2016 ed.
Volume:   396
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 11mm
Weight:   474g
ISBN:   9783319295541
ISBN 10:   3319295543
Series:   Current Topics in Microbiology and Immunology
Pages:   160
Publication Date:  
Audience:   College/higher education ,  Further / Higher Education
Format:   Hardback
Publisher's Status:   Active

Thomas J. Inzana is a Tyler J. and Frances F. Young Professor of Bacteriology and works at Virginia Tech School of Medicine in Blacksburg, VA, USA.

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