This book provides an essential update on the startling array of novel insecticidal toxins and drugs produced by the fascinating bacterium Photorhabdus. The respective chapters describe everything from the detailed molecular biology of the ‘Toxin complexes’ or Tc’s to the complexity of insect immune response in relation to both the bacterium and its nematode vector. The volume covers both primary (toxin production and regulation) and secondary (natural product synthesis and regulation) metabolism and emphasises the potential use of toxins and drugs in both agriculture and medicine. It also discusses in detail two totally novel quorum sensing mechanisms and the likely role of LuxR solos in sensing the presence of different bacterial hosts. Lastly, the book explores the unique case of P. asymbiotica, which seems to have evolved the ability to infect both insects and humans. This synthesis proves that Photorhabdus truly does offer a ‘gold mine’ for the discovery ofnovel insecticidal proteins and novel natural products with potential uses in agriculture and medicine alike.
Edited by:
Richard H. ffrench-Constant Imprint: Springer International Publishing AG Country of Publication: Switzerland Edition: 1st ed. 2017 Volume: 402 Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 14mm
Weight: 4.616kg ISBN:9783319527147 ISBN 10: 3319527142 Series:Current Topics in Microbiology and Immunology Pages: 213 Publication Date:07 June 2017 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active