Hepatitis C Virus

From Laboratory to Clinic

Mark A. Feitelson (Thomas Jefferson University, Philadelphia)

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English

Cambridge University Press
07 June 2002

Hepatology; Medical microbiology & virology

Hepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.

By: Mark A. Feitelson (Thomas Jefferson University Philadelphia)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Dimensions: Height: 248mm, Width: 174mm, Spine: 16mm
Weight: 582g
ISBN: 9780521799591
ISBN 10: 0521799597
Pages: 270
Publication Date: 07 June 2002
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Mark A. Feitelson, Ph.D. is currently Professor in the Department of Pathology, Anatomy and Cell Biology. He has a secondary appointment in the Department of Microbiology and Immunology and is a member of the Kimmel Cancer Center at Thomas Jefferson University. In addition, he is head of the Molecular Diagnostics Laboratory in Microbiology for Thomas Jefferson University Hospital. Prior to his transfer to Jefferson Medical College, Dr Feitelson trained with the nobel laureate Dr Baruch S. Blumberg at the Fox Chase Cancer Center. Dr Feitelson has been working on the biology and pathogenesis of hepatitis B for more than 20 years, and has recently started a similar research program in hepatitis C.

Reviews for Hepatitis C Virus: From Laboratory to Clinic

'The diligent reader of this book will come away with a thorough grounding in the virology and immunopathology of hepatitis C, know what the major sources of further information are, and understand why this infection is at once enigmatic, insidiously progressive, difficult to treat and hard to immunize against. Thoroughly recommended! Epidemiology and Infection Clinicians wishing for a brief but comprehensive summary of the current state of the art in laboratory-based investigation of HCV and HCV infection will find this book an excellent place to start. New England Journal of Medicine