In the animal nervous system, a very high metabolic turnover, fragile but steep ionic gradients, and morphological and structural constraints - dictated by the necessity for prompt neuronal transmission of electrical impulses and necessary plasticity - result in a highly fragile organ system. Here, we address a small sampling of major constituents of neural function at the cellular and molecular level that play important roles in development and aging, two endogenous processes that embody features of allostasis or the dynamic shifts in set points for specific homeostatic mechanisms associated with development and aging. These chapters stress the dynamic features of neuronal responses to internal (developmental) cues or the more harmful external events (injury and disease) in a modern perspective.
Edited by:
Regino Perez-Polo, Steffen Roßner Editor-in-chief:
Abel Lajtha Imprint: Springer-Verlag New York Inc. Country of Publication: United States Edition: 3rd ed. 2008 Dimensions:
Height: 240mm,
Width: 165mm,
Spine: 19mm
Weight: 670g ISBN:9780387326702 ISBN 10: 0387326707 Pages: 324 Publication Date:06 June 2008 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active