Fundamentals of Brain Organoids for Neurological Diseases

Dr. Balachandar Vellingiri mainly works on neurological diseases and analyzing its genetic impact. He is working on various neurological diseases to investigate the molecular mechanism and developing human induced pluripotent stem cells (HiPSCs), and generating patient-derived Brain organoids as a promising disease model for various neurological diseases because understanding the inside mechanism of neurological diseases is always a difficult task. Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. He is well-expertise in techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases. He has published over 100 research and review articles in various Internationally reputed SCI journals, 12 Book chapters and one book on Autism Spectrum Disorder. Dr Mahalaxmi Balachandar has experience in handling neurological disorder patients and has conducted genetic and epigenetic studies. She has experience in handling bone marrow derived mesenchymal stem cells (BM-MSCs) as a promising therapeutic agent for LHON disease. Further, Dr Mahalaxmi Balachandar has generated Brain organoids from various neurodevelopmental diseases. Her role in terms of research is to continually engage in research and update my knowledge to inspire the students to do their own original research. She has published almost 50 review and research articles in several internationally reputed SCI journals. Her articles in reputable international journals demonstrate how performing cutting edge research is made possible by updating current research technologies.