Management of Moderate or Severe Traumatic Brain Injury

Saeed Kayhanian (University of Cambridge), Erta Beqiri (University of Cambridge), Ari Ercole (University of Cambridge) , Adel Helmy (University of Cambridge)

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English

Cambridge University Press
12 June 2025

Neurology & clinical neurophysiology; Neurosurgery

Series: Elements in Emergency Neurosurgery

The management of patients with moderate and severe traumatic brain injury (TBI) is centred on the intensive care management to limit the extent of secondary injury to the brain, following the primary trauma. This management aims to optimise the homeostatic environment of the brain after injury and can be guided by multi-modality monitoring, including intracranial pressure (ICP) monitoring. This management often follows a tiered approach to introducing more aggressive interventions to correct physiology, based on evidence for ongoing secondary injury, such as raised ICP. The balance between risk and benefit for these interventions for individual patients is difficult, particularly in the absence of high quality randomised trials for many interventions in this area. In this Element, the authors outline both the approach to intensive care management of moderate and severe TBI, as well as the evidence base available for the interventions discussed.

By: Saeed Kayhanian (University of Cambridge), Erta Beqiri (University of Cambridge), Ari Ercole (University of Cambridge), Adel Helmy (University of Cambridge)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Weight: 62g
ISBN: 9781009437707
ISBN 10: 1009437704
Series: Elements in Emergency Neurosurgery
Pages: 26
Publication Date: 12 June 2025
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Intensive care management – general measures; ICP; Tiered ICP management strategy; Multimodality monitoring; Conclusion.