Exploring and Exploiting Genetic Risk for Psychiatric Disorders

Joshua A. Gordon, Elisabeth Binder

$100

Paperback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

MIT Press
14 November 2023

Criminal or forensic psychology; Mental health services; Psychiatry; Eating disorders & therapy

Series: Strüngmann Forum Reports

An edited volume that looks at the state of psychiatric genetics and how to chart a path forward.

An edited volume that looks at the state of psychiatric genetics and how to chart a path forward.

In this edited collection, experts from psychiatric and statistical genetics, neurobiology, and clinical psychiatry investigate whether and how to pursue the discovery of additional genetic risk factors for mental illnesses. Using the existing knowledge and frameworks of genetic risk factors, they look at how a better understanding of the biology that underlies mental illnesses can improve and enhance the care that patients receive.

Edited by: Joshua A. Gordon, Elisabeth Binder
Imprint: MIT Press
Country of Publication: United States
Volume: 31
Dimensions: Height: 229mm, Width: 154mm, Spine: 15mm
Weight: 448g
ISBN: 9780262547383
ISBN 10: 0262547384
Series: Strüngmann Forum Reports
Pages: 340
Publication Date: 14 November 2023
Audience: General/trade , ELT Advanced
Format: Paperback
Publisher's Status: Active

List of Contributors vii Preface xi 1 Exploring and Exploiting Genetic Risk for Psychiatric Disorders 1 Gene Discovery 2 Delineating Additional Risk Factors 13 3 Data Collection: Next Steps in Psychiatric Genetics 39 4 Environmental Risk and Gene-Environment Relationships in Psychiatric Disorders 51 Understanding Rare Variation 5 Rare Variants: Shared Paths for Therapeutic Development and Neurobiological Investigation 69 6 Promises and Challenges of Precision Medicine in Rare Neurodevelopmental Disorders 103 7 Experimental Model Systems for Rare and Common Variants 117 Understanding Common Variation 8 Common Alleles: Next Steps in the Study of Common Variants 131 9 Hypotheses of How Common Variants Create Risk for Psychiatric Disorders 155 10 From Common Variant to Function: State-of-the-Art Approaches 167 11 Contextualizing Convergent Common Variant Mechanisms through Systems Biology 179 Clinical Considerations 12 Maximizing Near-Term Clinical Opportunities for Psychiatric Genetics 201 13 The Use of Polygenic Risk Scores in Clinical Psychiatry: Opportunities and Obstacles 219 14 Ethical Challenges Associated with Advances in Genetic Prediction of Neuropsychiatric Disorders 237 15 Psychiatric Genetic Counseling: Next Steps 249 16 Concluding Summary 261 Bibliography 267 Subject Index 319 Strungmann Forum Report Series 325

Joshua A. Gordon is Director of the National Institute of Mental Health (NIMH) and Chief of the Integrative Neuroscience Section at the National Institute of Neurologic Disorders and Stroke (NINDS). Elisabeth B. Binder is a director and scientific member at the Max Planck Institute of Psychiatry.