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Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury

Proceedings of the Fourth International Conference

K.V. Honn Lawrence J. Marnett (Vanderbilt University School of Medicine, Nashville, TN, USA) Santosh K. Nigam Edward A. Dennis

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Hardback

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English
Kluwer Academic / Plenum Publishers
31 December 1999
Since their discovery over 60 years ago, eicosanoids have come to represent a diverse family of bioactive lipid modulators, including prostaglandins, thromboxanes, leukotrienes, lipoxins, isoprostanes, hepoxilins, hydroxy acids, epoxy and hydroxy fatty acids. This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. In addition, the latest evidence over the last seven years has led to the identification of a number of receptors for these bioactive lipids. The new field of isoprostanes is also represented. It has become increasingly evident that eicosanoids play a critical role in signal transduction, both in normal cells and in pathological processes. These aspects are discussed in relation to cellular events, such as apoptosis, angiogenesis, and cancer prevention and treatment.
Edited by:   , , , , , ,
Imprint:   Kluwer Academic / Plenum Publishers
Volume:   v. 469
Dimensions:   Height: 230mm, 
ISBN:   9780306461385
ISBN 10:   0306461382
Series:   Advances in Experimental Medicine and Biology
Pages:   710
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Hardback
Publisher's Status:   Active

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