Dermatopathology
The most up-to-date edition of a pattern-based dermatopathology atlas
In Dermatopathology: Diagnosis by First Impression, an expert team of dermatopathologists deliver an authoritative guide to the microscopic differentiation of visually similar dermatological diseases that is useful for both trainees and practicing physicians. This latest fourth edition includes new sections on alopecia and immunohistochemistry as well as over 100 new photomicrographs for a total of almost 1000 high-resolution and annotated figures.
The “Key Differences” pages walk the reader through the identification of distinctive diagnostic features, and disease-based and alphabetical indexes make it simple to quickly locate necessary information. Unique amongst dermatopathology atlases, this book remains organized by microscopic pattern???as opposed to disease category???which makes it the perfect companion for slide analysis. It also offers self-assessment questions and algorithms for pattern analysis, as well as:
An introduction to gestalt diagnosis Focus on architectural patterns as well as cell type/morphology Practical discussion of immunohistochemistry Expanded sections on melanocytic, soft tissue, and lymphoid lesions as well as alopecia
A visual feast for practicing dermatologists and pathologists, Dermatopathology: Diagnosis by First Impression will also earn a place in the libraries of trainees.
Preface, viii Acknowledgments, ix About the Companion Website, xi Introduction, 1 Chapter 1 Shape on Low Power, 23 Epidermis Regular acanthosis, 25 Lobular proliferation, 29 Reticulated proliferation, 35 Central pore, 42 Epidermal perforation, 46 Dermis Circular islands, 49 Cords/tubules and comma shapes, 53 Space with a lining, 59 Papillations, 70 Polypoid (dome-shaped), 77 Square/rectangular, 82 Palisading reactions, 88 Pseudoepitheliomatous hyperplasia above abscesses, 95 Pink ball, (see Chapter 6) Chapter 2 Gestalt: Rash/inflammatory, 99 Epidermal changes Parakeratosis, 101 Spongiosis, 104 Papulosquamous (psoriasiform), 108 Interface (vacuolar), 114 Interface (lichenoid), 119 Inflammation: Specific patterns and cell type Epidermal eosinophils, 125 Perivascular, 129 Band-like dermal/papillary dermal infiltrate, 133 Diffuse/nodular, 139 Subcutaneous, 146 Chapter 3 Cell Type, 153 Melanocytic, 155 Spindle cells, 168 Pleomorphic cells, 186 Epithelioid vs spindle vs pleomorphic cells, 187 Endothelial, 188 Giant, 202 Clear, 212 Chapter 4 Top-Down, 229 Arthropods, 231 Hyperkeratosis/parakeratosis, 237 Upper epidermal change, 244 Acantholysis, 254 Subepidermal space/cleft, 264 Granular “material” in cells, 271 “Busy” dermis, 276 Dermal material, 279 Fat necrosis, 292 Chapter 5 Color – Blue, 295 Blue tumor, 297 Lymphocytes, 307 Mucin and glands or ducts, 315 Mucin, 319 Chapter 6 Color – Pink, 327 Pink ball of spindle cells, 329 Pink material, 332 Pink dermis, 339 Epidermal necrosis, 341 Chapter 7 Miscellaneous, 347 Alopecia, 349 Immunohistochemistry, 354 Index (Pattern), 361 Index (Histological Category), 366 Index (Alphabetical), 369
Christine J. Ko, MD, is Professor of Dermatology and Pathology at Yale University. She is board certified in both dermatology and dermatopathology. She is the author of several academic texts in dermatology and dermatopathology, including Dermatology Essentials and Dermatology: Visual Recognition and Case??Reviews. Ronald J. Barr, MD, is Professor Emeritus of Dermatology and Pathology at University of California, Irvine. He??is board certified in anatomical pathology, dermatology, and dermatopathology. He is recognized for his many contributions in dermatopathology, involving both neoplastic and non-neoplastic disorders.
