Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

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Ingvar Eidhammer (University of Bergen, Norway) Harald Barsnes (Department of Biomedicine, University of Bergen, Norway)

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

Ingvar Eidhammer (University of Bergen, Norway), Harald Barsnes (Department of Biomedicine, University of Bergen, Norway), Geir Egil Eide (Centre for Clinical Research, Haukeland University, Norway) , Lennart Martens (European Bioinformatics Institute (EBI), Cambridge, UK)

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English

John Wiley & Sons Inc
04 January 2013

Probability & statistics; Spectrum analysis, spectrochemistry, mass spectrometry; Biochemistry

The definitive introduction to data analysis in quantitative proteomics

This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers.

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry:

Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods.

With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.

By: Ingvar Eidhammer (University of Bergen Norway), Harald Barsnes (Department of Biomedicine, University of Bergen, Norway), Geir Egil Eide (Centre for Clinical Research, Haukeland University, Norway), Lennart Martens (European Bioinformatics Institute (EBI), Cambridge, UK)
Imprint: John Wiley & Sons Inc
Country of Publication: United States
Dimensions: Height: 239mm, Width: 160mm, Spine: 23mm
Weight: 576g
ISBN: 9781119964001
ISBN 10: 1119964008
Pages: 360
Publication Date: 04 January 2013
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Ingvar Eidhammer, Department of Informatics, University of Bergen, Norway Harald Barsnes, Department of Biomedicine, University of Bergen, Norway Geir Egil Eide, Centre for Clinical Research, Haukeland University,Norway Lennart Martens, Department of Biochemistry, Faculty of Medicine and Health Sciences, Ghent University, Belgium

Reviews for Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry is a book that can be used by undergraduate students in both analytical chemistry and biochemistry, as well as by scientists who are familiar with the field. The book teaches the reader how to perform proteomic analysis by mass spectrometry and how to interpret the large amount of data collected. (Analytical and Bioanalytical Chemistry, 10 January 2014)