Protein Mutations

Consequences On Structure, Functions, And Diseases

M Michael Gromiha (Indian Inst Of Technology Madras, India)

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Hardback

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English

World Scientific Publishing Co Pte Ltd
28 October 2024

Biology, life sciences; Biochemistry

Summary
Details

Proteins perform various functions in living organisms. However, any mutation in the amino acid residues of a protein affects its structure and function. Some of these mutations may lead to diseases. These disease-causing mutations have an impact on protein structure, stability, and its binding affinity to complexes. Moreover, the study of amino acid mutation in proteins is important for developing therapeutic strategies. It is a pertinent and timely endeavor to provide comprehensive insights on the consequences of these mutations.

The main highlights of this book are the effects of protein mutations on its various functions such as aggregation, folding, stability, binding affinity, and diseases, as well as a wide range of applications such as database development, computational algorithms, and drug design. It will be a platform to provide the up-to-date information and latest developments in the field and will serve as a single resource to get the information on comparative studies to delineate these mutational effects on protein folding, stability, and interactions, and for understanding the molecular basis of diseases.

By: M Michael Gromiha (Indian Inst Of Technology Madras India)
Imprint: World Scientific Publishing Co Pte Ltd
Country of Publication: Singapore
ISBN: 9789811293252
ISBN 10: 9811293252
Pages: 396
Publication Date: 28 October 2024
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Hardback
Publisher's Status: Active