Biomaterials and Immune Response

Complications, Mechanisms and Immunomodulation

Nihal Engin Vrana (Protip Medical, Strasbourg, France)

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English

CRC Press
07 September 2018

Immunology; Biomedical engineering; Life sciences: general issues; Materials science; Environmental science, engineering & technology

Series: Devices, Circuits, and Systems

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials.

Provides keen insight into biomaterial–immune cell interactions

Presents an explanation of state-of-the-art methodologies in immunomodulation

Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic

Explores a comprehensive overview of biomaterial related complications

Provides extensive references at the end of each chapter to enhance study for this very hot research area

Edited by: Nihal Engin Vrana (Protip Medical Strasbourg France)
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 566g
ISBN: 9781138506374
ISBN 10: 1138506370
Series: Devices, Circuits, and Systems
Pages: 249
Publication Date: 07 September 2018
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Editorial: Biomaterials and Immune Response; Introduction to Immune Cells and Their Roles in Response to Biomaterials. Macrophange Plasticity and Foreing Body Response. The Effects of Biomaterials with Micro/Nanotopographies on Immune Cells in Vitro and in Vivo. Immune Response to Nanoparticles. Surface Chemistry and Immunce Response. Hyaluronic Acid as a Biomaterial and its Role in the Immune System. Bacterial Attachment and Biofilm Formation on Biomaterials: The Case of Dental and Orthopaedic Implants. Osteoimmunomodulation with Biomaterials. Macrophange Based Immunomodulation for Biomaterial Applications.

Dr. Nihal Engin Vrana is Vice-President of Scientific Affairs at PROTIP Medical. He obtained his PhD in 2009 at Dublin City University as a Marie Curie ESR Fellow. His major research interests are titanium implants, tissue engineering, cell encapsulation, immunodulation, real-time monitoring and implants and cell biomaterials and cell biomaterials interactions. He has published over 55 articles in peer reviewed academic journals, 4 book chapters and holds three European patents. He holds three ESB Translational Research Awards.