Allostery

Methods and Protocols

Luisa Di Paola, Alessandro Giuliani

$316.95 $253.52

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Springer-Verlag New York Inc.
15 December 2020

Proteins

Series: Methods in Molecular Biology

This volume explores the basic issues of “allostery” and “network” that are fundamental to studying this field. Chapters in this book look at how the basic “machine-like” proteins, that are similar to “human machines,” need to be organized, architecturally, to relate to different organizational layers. Chapters cover topics such as methodological/computational factors focused on links between allostery and network formalism; the presence of oscillating modes transversing the structure and underlying network wiring of the allosteric process; the “action at distance” by transduction of signals across an organized network structure; and the P53 protein located at the cross-road of cell cycle regulation, genome integrity, and cancer development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Thorough and practical, Allostery: Methods and Protocols is a valuable resource for any scientists and researcher interested in learning more about this developing field.

Edited by: Luisa Di Paola, Alessandro Giuliani
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States
Edition: 2021 ed.
Volume: 2253
Dimensions: Height: 254mm, Width: 178mm,
Weight: 743g
ISBN: 9781071611531
ISBN 10: 1071611534
Series: Methods in Molecular Biology
Pages: 274
Publication Date: 15 December 2020
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Allostery: The Rebound of Proteins.- Disclosing Allostery Through Protein Contact Networks.- Identification of Allosteric Effects in Proteins by Elastic Network Models.- Locating and Navigating Energy Transport Networks in Proteins.- Probing Allosteric Mechanism with Long-Range Rigidity Transmission across Protein Networks.- Protein Assembly: Defining the Strength of Protein-Protein Interactions Coupling the Theory with Experiments.- Network Re-Wiring during Allostery and Protein-Protein Interactions: A Graph Spectral Approach.- Topology Results on Adjacent Amino Acid Networks of Oligomeric Proteins.- Community Network Analysis of Allosteric Proteins.- The PyInteraph Workflow for the Study of Interaction Networks Form Protein Structural Ensembles.- The Allosteric Effect in Antibody-Antigen Recognition.- Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.- Investigating Conformational Dynamics and Allostery in the p53 DNA-Binding Domain Using Molecular Simulations.- Molecular Dynamics Simulation Techniques as a Tool in Drug Discovery and Pharmacology: A Focus on Allosteric Drugs.- Cooperativity and Allostery in RNA Systems.