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Advancement in Animal Handling and Generative AI for Pre-clinical Studies

Gurudutta Pattnaik Soumya Jal

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English
CRC Press
25 August 2025
AYUSH encompasses traditional Indian medical systems like Ayurveda, Yoga, Naturopathy, Unani, Siddha, and Homeopathy. The CCRAS, funded by AYUSH, supports research programs to scientifically validate traditional medicine’s efficacy. India’s Ministry of AYUSH promotes and regulates these practices, aiming for their integration into modern healthcare while preserving their cultural significance. Centurion University of Technology and Management (CUTM), established in 2010, offers quality education across various fields. Noteworthy for its holistic approach, CUTM emphasizes practical skills, industry collaboration, and societal contributions. It’s School of Pharmacy and Life Sciences, along with the School of Paramedics and Allied Health Sciences, lead in providing quality healthcare education, maintaining robust ecosystems to bolster healthcare facilities.
Edited by:   ,
Imprint:   CRC Press
Country of Publication:   United Kingdom
Dimensions:   Height: 229mm,  Width: 152mm, 
Weight:   460g
ISBN:   9781041140818
ISBN 10:   1041140819
Pages:   250
Publication Date:  
Audience:   College/higher education ,  Professional and scholarly ,  Primary ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
1 AI-driven mathematical modelling of perturbated cancer metabolic pathways: Predicting doxorubicin-induced PHGDH inhibition through the PI3K/Akt/mTOR pathway Victor Pradhan and Preetha Bhadra 2 Design and synthesis of novel benzimidazole-pyrazoline hybrid molecules as anticancer agent Gopal Krishna Padhy and Jagadeesh Panda 3 Ionic gelation technique using biodegradable polymer for stabilized and sustained oral delivery of nano protein Prasanna Parida, Amiya Kumar Prusty, Chinmaya Sahoo, Sujit Dash, Bikash Ranjan Jena, and Kirtimaya Mishra 4 Overcoming hurdles in oral protein and peptide drug delivery: Strategies for future prospective Prasanna Parida, Amiya Kumar Prusty, Rajat Kumar Prusty, Bikash Ranjan Jena, Debabrata Panda, and Sanjoy Das 5 The impact of mirror therapy in improving hand motor function following stroke DattaSai Pamidimarri, Nagarjuna Narayansetti, Preety Kumari, SriKavya Grandhi, Soumya Saswati Panigrahi, and Ravi Kumar Kalari 6 Modifying the triphasic liver CT scan protocol to achieve optimal vascular contrast Aswathi P., Abhijith S., Anushka Valeska Fernandes, and Jayeeta Dandapat 7 Network pharmacology and molecular docking analysis for elucidation of mechanism of action and molecular targets of Commiphora wightii in treatment of atherosclerosis Sangeeta Chhotaray, Kanika Verma, Pralaya Kumar Sahoo, and Soumya Jal 8 Investigating the potential of medicinal plant essential oils as a powerful medication B. Jyotirmayee, Ipsita Priyadarsini Samal, Sameer Jena, and Gyanranjan Mahalik 9 Profiling of bioactive compounds in methanolic leaf extract of Artemisia nilagirica (C.B.Cl) Pamp. through GC-MS and In-silico study of some selected compound Sagorika Panda, Kalpita Bhatta, Himansu Bhusan Samal, and Pratikshya Mohanty 10 Design and development of Psidium Guajava Leaf extract loaded topical emulgel Sk Hasibur Ali, Sonalika Mahapatra, Tamosa Mukherjee, Mamalisa Sahoo, Monali Priyadarshini Mishra, Himanshu Bhusan Samal, and Yashwant Giri 11 Design and development of topical herbal antimicrobial gel loaded with cadamba leaf extract Kuldip Singh, Tamosa Mukherjee, Sonali Bhujabal, Yashwant Giri, Gurudutta Pattnaik, Amulyaratna Behera, and Biswaranjan Mohanty 12 Development of in-situ ocular gel containing topiramate to understand its effect in intraocular pressure Biswajeet Puhan, Aradhana Panigrahi, Guptanjali Sahu, Yashwant Giri, Bikash Ranjan Jena, and Gurudutta Pattnaik 13 Formulation and evaluation of Amphotericin-B loaded topical antifungal organogel Rozalika Mohanty, Himansu Bhusan Samal, Aradhana Panigrahi, Yashwant Giri, and Gurudutta Pattnaik 14 Formulation and evaluation of vildagliptin loaded in-situ gel for ocular drug delivery: An improved approach towards management of diabetic retinopathy Pritish Kanungo, Subhashree Das, Debaprasad Routray, Guptanjali Sahu, Yashwant Giri, and Gurudutta Pattnaik 15 Design, optimization and evaluation of telmisartan fast dissolving film employing mango kernel starch as a new natural super disintegrant Medisetty Gayatri Devi, Santosh Kumar R., and Anusha Kusuma 16 Deeper and updated insights on breast cancer Anup Kumar Dash and Sucharita Babu 17 UV-visible spectrophotometric method for estimation of Tacrolimus in bulk and different pharmaceutical capsules Babita Adhikary and Ladi Alik Kumar 18 Recent advancement in targeted drug delivery systems for cancer treatment: Updated review Jyoshna Rani Dash, Omprakash Pradhan, Rajesh Kumar Pradhan, Gurudutta Pattnaik, and Biswakanth Kar 19 IONPs as strategic nanotools for cancer therapy: Concise updates on facile synthetic methods and stabilization Jnanranjan Panda, Sagar Rout, Gurudutta Pattnaik, Himansu Bhusan Samal, Bikash Ranjan Jena, and Bhabani Sankar Satapathy 20 Development of stability indicating RP-HPLC method for simultaneous estimation of sacubitril and valsartan in pure and pharmaceutical dosage form Kumar Dhiraj and Himansu Bhusan Samal 21 Development of sophisticated RP-HPLC approach for quantifying lornoxicam in API and pharmaceutical formulation Biswa Mohan Sahoo, Chandan Kumar Brahma, Bikash Ranjan Jena, Kirtimaya Mishra, Debabrata Panda, Satya Narayan Tripathy, and Dipika Rani Sahu 22 COVID-19: Immergence, molecular mechanism of transmission and pathogenesis Chinmaya Chidananda Behera, Sagar K Mishra, Biswajit Mishra, Gurudutta Pattnaik, Bikash Ranjan Jena, and Suman K Mekap

Dr. Gurudutta Pattnaik gained his BPharm from PES College of Pharmacy, Bangalore in 1996, MPharm from University Department of Pharmaceutical Sciences, Utkal University, Bhubaneswar, in 2001 and Doctoral degree from Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India. Having over 25 years of UG and PG teaching experience he served various faculty positions at various Pharmacy Institutions of high repute in India and abroad, like National Institute of Pharmaceutical Education & Research (NIPER), Raebareli, India and College of Health Science, Mekelle University, Ethiopia. His area of Research Interest includes Nanoparticle, Liposomal drug delivery, Pharmacokinetics etc. He has supervised 9 PhD scholars under CUTM and 01 under BPUT, Odisha, Convenor in DST-SERB, ICMR sponsored National Seminars, Evaluator, Question paper setter at NIPER, Raebareli, India. He also served as Resource persons in various National and International Conference, QIPs and published papers, Book chapters in reputed indexing high impact factor journals. Dr. Soumya Jal is currently serving as the Associate Professor and Dean of the School of Paramedics and Allied Health Sciences, Centurion University of Technology and Management (Odisha). With over a decade of experience in healthcare education and research, Dr. Jal has made significant contributions to the field, particularly in healthcare management and biotechnology. She holds a PhD in Biotechnology from Vellore Institute of Technology University, Vellore, with her research focusing on the tetrodotoxin profile of puffer fish and its bacterial origins in eastern India. She has published extensively in reputed journals and contributed chapters to significant academic books. Her expertise includes clinical biochemistry, immunology, microbiology, and molecular biology techniques. Throughout her career, Dr. Jal has been recognized with several awards and achievements, including a Research Award from VIT University and a Merit Scholarship Award for outstanding academic performance. She is also actively involved in interdisciplinary collaborations and initiatives aimed at improving healthcare delivery and outcomes. She has chaired a session at the 3rd GSN Conference and acted as a Jury member at ICMSE 2024 international conference. Dr. Soumya Jal has held several prestigious academic positions in her career. She has served as HoD (SoPAHS); Disciplinary Committee member; Nodal Officer from CUTM at Board of Practical Training (Ministry of Higher Education, GOI). Dr. Himansu Bhusan Samal, MPharm, PhD, FIC is working as Associate Professor & Associate Dean, in School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha. Prior to working at Centurion University, he was working as Assistant Professor at Guru Nanak Institutions Technical Campus-School of Pharmacy (An Autonomous Institution under UGC, NBA, NAAC A+ Accredited), Ibrahimpatnam, Hyderabad. He is having 16 years of experience in Teaching and Research. Currently he is working as. He has published 40 scientific research papers in international and national peer reviewed journals. He has also published 6 book chapter and 7 patents. He is a life member of APTI and has guided more than 30 M. Pharm students. Currently guiding 5 PhD research scholars. His primary research interest are in the field of Periodontal drug delivery, wound healing, solubility and dissolution rate enhancement, nanoparticulate drug delivery, and mucoadhesive drug delivery. Dr. Kirtimay Mishra Prof. is a young and dynamic professor cum researcher. He completed his PhD, from Annamalai University, Chidambaram, India. He completed his Master of Pharmacy from Berhampur University, Berhampur, Odisha, India; and Bachelor of Pharmacy as well as Diploma in Pharmacy from Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, India. He is meritorious student during his studies. Currently he is working as Professor in Centurion University, Department of Pharmacy, Bhubaneswar, Odisha, India. Prof. (Dr.) Kirtimaya Mishra has 14 years of research and teaching experience. He has published many articles at national/international journals of repute. He has pre>sented his research work at national/international conferences and attended more than 250 conferences/seminars/workshops. He has guided 14 MPharm students to carry out their research work and 4 PhD students continuing research under his guidance. He has developed some new methods for analytical validation using Quality by Design technology. He is expertise in analytical instruments handling like HPLC, LC-MS/MS, HPTLC, UV-Visible Spectrophotometer etc. Dr. Bikash Ranjan Jena is Associate Professor at Centurion University, Bhubaneswar, Odisha, India. He has a total 13 years of academic and research experience. He has published 85+ research papers, edited 4 international textbooks, 35+ book chapters, 37 in Scopus, 18+ WoS, articles. He holds H index 10 in Google Scholar, 8 in Scopus. He received the Young Achiever Award in 2021 from the Institute of Scholars (InSc), India, Received ‘Faculty Performer Award-2023’ and ‘Research Incentive Award’- 2022 from Centurion University for his article contributions. He is a life member of the Association of Pharmaceutical Teachers of India, the Indian Association of Nuclear Chemists and Allied Scientists, and the Asian Council of Science

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