Treatment and Prevention of Malaria

Antimalarial Drug Chemistry, Action and Use

Henry M. Staines, Sanjeev Krishna

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Hardback

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English

Birkhauser Verlag AG
06 January 2012

Infectious & contagious diseases; Immunology; Medical parasitology; Pharmacology

Series: Milestones in Drug Therapy

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.

Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Edited by: Henry M. Staines, Sanjeev Krishna
Imprint: Birkhauser Verlag AG
Country of Publication: Switzerland
Edition: 2012
Dimensions: Height: 235mm, Width: 155mm, Spine: 23mm
Weight: 658g
ISBN: 9783034604796
ISBN 10: 3034604793
Series: Milestones in Drug Therapy
Pages: 318
Publication Date: 06 January 2012
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Reviews for Treatment and Prevention of Malaria: Antimalarial Drug Chemistry, Action and Use

From the reviews: “Staines and Krishna successfully captures the essence of what we know about antimalarials at the beginning of the second decade of the 21st century. … the book is a welcome and highly valuable documentation on where we stand and offers valuable food for thought in the search for the way forward.” (Martin P. Grobusch, Trends in Parasitology, September, 2012)