Transgenic Animals

Louis-Marie Houdebine

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English

Taylor & Francis Ltd
22 May 1997

Genetics (non-medical); Animal reproduction; Genetic engineering

During the past 20 years, transgenesis has become a popular technique and a crucial tool for molecular geneticists and biologists. Transgene expression is now better-controlled and even specifically inducible by exogenous factors. While these techniques have quite significantly transformed the experimental approaches taken by biologists, the applications are more limited than expected and concerns have arisen regarding biosafety as well as physiological, social, and philosophical issues.

Transgenic Animals: Generation and Use contains articles on the techniques used to generate transgenic animals and a section on the preparation of vectors for the optimally controlled expression of transgenes. It also examines the use of transgenic animals in the study of gene function and human diseases, the preparation of recombinant proteins and organs for pharmaceutical and medical use, and the improvement of genetic characteristics of farm animals. Finally, it discusses more recent problems generated by transgenic animals including conservation of transgenic lines, specific database patenting, biosafety, and bioethics.

Drawn from both academia and industry, the contributors to this monograph present in one concise volume all the relevant information on the different aspects of transgenesis. This book can be used as both a reference book and a textbook for specialized university courses and will be of interest to everyone involved in basic research in animal biology, molecular genetics, animal biotechnology, pharmaceutical science, and medicine.

By: Louis-Marie Houdebine
Imprint: Taylor & Francis Ltd
Country of Publication: United Kingdom
Dimensions: Height: 280mm, Width: 210mm, Spine: 25mm
Weight: 1.460kg
ISBN: 9789057020698
ISBN 10: 9057020696
Pages: 592
Publication Date: 22 May 1997
Audience: College/higher education , Professional and scholarly , Further / Higher Education , Undergraduate
Format: Paperback
Publisher's Status: Active

Overview. The Techniques for Gene Transfer. The Fate of Microinjected DNA into Mammal Embryos. The Use of Transgenic Animals. The New Problems Generated by Transgenic Animals.

Louis-Marie Houdebine (Unite De Diff Cellulaire, Jouy-En-Josas, France) (Author)