Torsades de Pointes

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James E. Tisdale (Professor, College of Pharmacy, Purdue University; Adjunct Professor, School of Medicine, Indiana University, Indianapolis, IN, USA)

Torsades de Pointes

James E. Tisdale (Professor, College of Pharmacy, Purdue University; Adjunct Professor, School of Medicine, Indiana University, Indianapolis, IN, USA)

$290.95

Paperback

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English

Academic Press Inc
17 March 2022

Cardiovascular medicine

Over the past 25-30 years, deaths due to Torsades de Pointes (TdP) have resulted in numerous drugs being withdrawn from the market. However, nearly 200 drugs that may prolong the QT interval and cause TdP remain available. A number of drugs with the potential to cause TdP are among the top 200 most prescribed drugs in the US, whilst new information regarding TdP is emerging rapidly. The purpose of this book is to provide a comprehensive source of information on the topic of torsades de pointes (TdP), which is a life-threatening polymorphic ventricular tachyarrhythmia associated with QT interval prolongation on the electrocardiogram (ECG).

Torsades de Pointes provides a detailed, up-to-date and emerging information related to the epidemiology, drug culprits, mechanisms, risk factors, and methods of prevention and management of the life-threatening polymorphic ventricular tachycardia, also known as torsades de pointes. The book contains current knowledge, incorporating recent and cutting-edge advances in understanding of topics including inherited channelopathies and congenital LQTS; drugs that cause QT interval prolongation and TdP; non-drug causes of acquired QT interval prolongation and TdP; epidemiology of inherited and acquired TdP; morbidity and mortality associated with TdP, particularly in association with specific antimicrobials, antidepressants and antipsychotics, and methadone; cellular and molecular mechanisms of TdP, traditional and emerging risk factors for TdP; methods of prevention and risk reduction for TdP; and clinical management of patients with TdP.

This book is an essential reference for both clinicians and researchers – providing guidance for clinicians who care for patients receiving QT interval-prolonging drugs, as well as cutting edge information for scientists and investigators conducting research in the area.

Edited by: James E. Tisdale (Professor College of Pharmacy Purdue University; Adjunct Professor School of Medicine Indiana University Indianapolis IN USA)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 276mm, Width: 216mm,
Weight: 1.020kg
ISBN: 9780128214466
ISBN 10: 0128214465
Pages: 376
Publication Date: 17 March 2022
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Prof. Tisdale is a Professor of Pharmacy at Purdue University and an Adjunct Professor under the School of Medicine at Indiana University. His main research focus is studying drugs that cause torsades de pointes (TdP) and methods of prevention and reducing the risk of drug-induced TdP. He has published more than 100 journal articles and book chapters, with an emphasis on the topic of drug-induced QT interval prolongation and TdP. He is also a fellow of the American Heart Association, the American College of Clinical Pharmacy, the American Pharmacists Association, and the National Academies of Practice.

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Torsades de Pointes

James E. Tisdale (Professor, College of Pharmacy, Purdue University; Adjunct Professor, School of Medicine, Indiana University, Indianapolis, IN, USA)

$290.95

Paperback

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