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The Road from Nanomedicine to Precision Medicine

Shaker A. Mousa Raj Bawa Gerald F. Audette



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Pan Stanford Publishing Pte Ltd
12 February 2020
The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines-all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book's multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.
Edited by:   Shaker A. Mousa, Raj Bawa, Gerald F. Audette
Imprint:   Pan Stanford Publishing Pte Ltd
Country of Publication:   Singapore
Dimensions:   Height: 229mm,  Width: 152mm, 
Weight:   2.286kg
ISBN:   9789814800594
ISBN 10:   9814800597
Series:   Jenny Stanford Series on Nanomedicine
Pages:   1208
Publication Date:   12 February 2020
Audience:   College/higher education ,  Professional and scholarly ,  Primary ,  Undergraduate
Format:   Hardback
Publisher's Status:   Active
PART A Drug Delivery at the Nanoscale: A Guide for Scientists, Physicians and Lawyers Raj Bawa, MS, PhD What Is Precision Medicine? A Primer on Contemporary Issues and Concerns Kadija Ferryman, PhD, and Mikaela Pitcan, PhD FDA's Role in Paving the Way for Personalized Medicine U.S. Food and Drug Administration Multifunctional Gold Nanoparticles in Drug Delivery Systems Zachary I. Stryker, Mehdi Rajabi, PhD, and Shaker A. Mousa, PhD Nanoparticles and Nanoparticulate Drug Delivery Systems: Impact of Size and Structure on Functionality Ajit S. Narang, PhD, Rong-Kun Chang, PhD, and Munir A. Hussain, PhD Self-Assembling Peptide Amphiphiles as a Versatile Future Nanomedicine Platform Run Chang, MS, and Thomas J. Webster, PhD Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery Schuyler A Pruyn, BSc, Mehdi Rajabi, PhD, Mary Adeyeye, BSc, and Shaker A. Mousa, PhD Nanomaterials: Tools, Technology, and Methodology of Nanotechnology-Based Biomedical Systems for Diagnostics and Therapy Christian Schmidt, PhD, and Joachim Storsberg, PhD Nanomagnetic Resonance Imaging (Nano-MRI) Gives Personalized Medicine a New Perspective Lorenzo Rosa, PhD, Jonathan Blackledge, and Albert Boretti, PhD Advancing Precision Medicine: Tailoring Personalized Therapies Kyle B. Matchett, PhD, Niamh Lynam-Lennon, PhD, R. William Watson, PhD, and James A. L. Brown, PhD Precision Medicine for Alzheimer's Disease Prevention Cara L. Berkowitz, BA, Lisa Mosconi, PhD, Olivia Scheyer, BA, Aneela Rahman, BA, Hollie Hristov, FNP, and Richard S. Isaacson, MD Advanced Porphyrin Nanomaterials for Biological Applications Haoyuan Huang, PhD, and Jonathan F. Lovell, PhD Cerium Oxide Nanoparticles as a Novel Reactive Oxygen Modulating Nanodrug Ece Alpaslan, PhD, and Thomas J. Webster, PhD Artificial Nanomachines and Nanorobotics Alexandre Loukanov, PhD, DSc, Hristo Gagov, PhD, and Seiichiro Nakabayashi, PhD Nanomotors for Nucleic Acid, Protein, Pollutant, and Cell Detection Alejandro Baeza, PhD, and Maria Vallet-Regi, PhD Magneto-Responsive Scaffolds for Tissue Engineering Applications Adedokun A. Adedoyin, PhD, and Adam K. Ekenseair, PhD Anti-Cancer and Anti-Angiogenic Properties of Nano-Diamino-Tetrac, A Thyroid Hormone Derivative Paul J. Davis, MD, and Shaker A. Mousa, MBA, PhD PART B Proteomic Profiling and Predictive Biomarkers in Neuro-Traumatology and Neuro-Oncology Mario Ganau, MD, PhD, Nikolaos Syrmos, MD, MSc, Marco Paris, MD, and Lara Prisco, MD, MSc Nanomedicine and Personalized Care: Facts and Fiction David M. Berube, PhD and Emily Winderman, PhD Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer Jiajia Zhang, MD, MPH, Christopher L. Wolfgang, MD, MS, PhD, and Lei Zheng, MD, PhD Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment Vivek Podder, MBBS, Binod Dhakal, MD, Gousia Ummae Salma Shaik, MD, Kaushik Sundar, DM, Madhava Sai Sivapuram, MBBS, Vijay Kumar Chattu, MD, and Rakesh Biswas, MD Views from the FDA: Precision Medicine, Genetic Variant Databases and Companion Diagnostics U.S. Food and Drug Administration Protein-Based Nanoparticle Materials for Medical Applications Kelsey DeFrates, BSc, Theodore Markiewicz, BSc, Pamela Gallo, BSc, Aaron Rack, BSc, Aubrie Weyhmiller, BSc, Brandon Jarmusik, BSc, and Xiao Hu, PhD Nanomedicine and Phage Capsids Philip Serwer, PhD, and Elena T. Wright Pharmacogenomics: Ethical, Social, and Public Policy Issues Yann Joly, PhD, and Denise Avard, PhD From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology Maria Eugenia Gallo Cantafio, PhD, Katia Grillone, PhD, Daniele Caracciolo, MD, Francesca Scionti, PhD, Mariamena Arbitrio, MD, Vito Barbieri, MD, Licia Pensabene, MD, Pietro Hiram Guzzi, PhD, and Maria Teresa Di Martino, PhD Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs Janet L. Williams, MS, Wendy K. Chung, MD, PhD, Alex Fedotov, PhD, Krzysztof Kiryluk, MD, Chunhua Weng, PhD, John J. Connolly, PhD, Margaret Harr, MS, Hakon Hakonarson, MD, PhD, Kathleen A. Leppig, MD, Eric B. Larson, MD, Gail P. Jarvik, MD, PhD, David L. Veenstra, Pharm D, PhD, Christin Hoell, MS, Maureen E. Smith, MS, Ingrid A. Holm, MD, MPH, Josh F. Peterson, MD, MPH, and Marc S. Williams, MD Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine Tetsuya Fujimura, MD, PhD, Kenichi Takayama, MD, PhD, Satoru Takahashi, MD, PhD, and Satoshi Inoue, MD, PhD Precision or Personalized Medicine for Cancer Chemotherapy: Is There a Role for Herbal Medicine? Zhijun Wang, PhD, Xuefeng Liu, MD, Rebecca Lucinda Ka Yan Ho, MSc, Christopher Wai Kei Lam, PhD, and Moses Sing Sum Chow, PharmD Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine Roy C. Ziegelstein, MD Stem Cell Banking for Regenerative and Personalized Medicine David T. Harris, PhD Overview of Ethical Issues in Nanomedicine Raj Bawa, MS, PhD, and Summer Johnson, PhD Amphiphilic Nanocarrier Systems for Curcumin Delivery in Neurodegenerative Disorders Miora Rakotoarisoa, MS, and Angelina Angelova, PhD Peptide-Based Drug Delivery Systems: Future Challenges, Perspectives, and Opportunities in Nanomedicine Diego Tesauro, PhD, Antonella Accardo, PhD, Carlo Diaferia, PhD, Vittoria Milano, PhD, Jean Guillon, PhD, Luisa Ronga, PhD, and Filomena Rossi, PhD Hydrogels and Their Applications in Targeted Drug Delivery Radhika Narayanaswamy, MSc, and Vladimir P. Torchilin, PhD, DSc Emergence of Real World Evidence in Precision Medicine Neil A. Belson, MS, JD

Shaker A. Mousa, PhD is an endowed chair, tenured professor of Pharmacology at Albany College of Pharmacy; Vice Provost of Research, executive vice president, and chair of Pharmaceutical Research Institute at Albany, NY. Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, VA, USA that he founded in 2002. Gerald F. Audette, PhD, is an Associate Professor in the Department of Chemistry and member of the Centre for Research on Biomolecular Interactions at York University in Toronto, Canada.

Reviews for The Road from Nanomedicine to Precision Medicine

The carefully-selected range of topics in this masterpiece will be equally beneficial to academia, physicians, drug industry, business, healthcare systems, policymakers, geneticists, regulatory bodies and governments. In the coming decade efforts in nanomedicine and precision medicine will be translated from the bench to the bedside, paving the way for more accurate diagnosis and more precise therapeutics. This review volume is a standard reference resource for anyone involved in the coming healthcare revolution. Tatiana K. Bronich, University of Nebraska Medical Center, USA The first 3 volumes in this series have been inspirational and form the most definitive and useful references for anyone wishing to know about the technical, clinical, legal, business and regulatory aspects of nanomedicine. The topic has in the past raised expectations to levels that were probably too high, but anyone reading these books will understand the opportunities and barriers much better. This fourth volume was awaited with great interest. Peter J. Dobson, University of Oxford, UK It is wonderful to see that Nobel Laureate Paul Ehrlich's vision of magic bullets postulated in 1908 may eventually be fully realized along the road from nanomedicine to precision medicine. The power unleashed by elucidation of the genome coupled with the elegance of site-specific drug delivery will revolutionize healthcare in the next century. In my 70-years as a researcher and university professor, nothing has held a greater potential to diagnose and treat diseases in a more customizable, targeted manner. This masterful volume reflects the innovative developments, potential applications and possible bottle-necks in these two interrelated fields. S. R. Bawa, Panjab University, India Precision medicine and targeted nanomedicines are the Holy Grail of medicine and drug delivery; this comprehensive volume highlights their salient features and interconnectivity. A team of distinguished editors and authors have done a superb job focussing on the critical and current issues, masterfully dissecting hype from reality. Janos Szebeni, Semmelweis University School of Medicine, Budapest, Hungary The growth, opportunity and promise of nanomedicine has become breathtaking which is why The Road from Nanomedicine to Precision Medicine by Mousa, Bawa and Audette is my go to reference. It puts cutting-edge nano-developments in context of personalized/precision medicine and the lessons learned from applications in one clinical challenge may serve as a template for other challenges. Use this volume as a reference but be sure to read it for inspiration. Nicholas Borys, Celsion Corporation, New Jersey, USA As nanomedicine begins to mature further and evolves towards enabling precision medicine, this volume with its punctiliously selected content is destined to become a must-have reference resource. The editors have made an astounding effort that connects different manifestations of nanomedicines with the many modes of developing precision medicine, while illuminating the regulatory pathway and challenges therein for all of us to learn from. Its unique contents will be especially useful to oncology, infectious diseases, degenerative diseases and regenerative medicine. Anil R. Diwan, PhD, NanoViricides, Inc., Connecticut, USA The untapped solutions from nanotechnology will enable breakthroughs in customized healthcare. This comprehensive edition provides the groundwork of where nanomedicine will lead to tailoring precision medicine for individual patient care. Neil Gordon, Guanine Inc., New York, USA

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