The Pacemaker Channels Of The Heart: From Reductionism To Systems Biology

— —

Denis Noble (University Of Oxford, Uk & Daegu Gyeongbuk Inst Of Science And Technology, South Korea)

The Pacemaker Channels Of The Heart

From Reductionism To Systems Biology

Denis Noble (University Of Oxford, Uk & Daegu Gyeongbuk Inst Of Science And Technology, South Korea)

$238.95 $191.55

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

World Scientific Europe Ltd
10 November 2025

Physiology; Cardiovascular medicine

Summary
Details

In The Pacemaker Channels of the Heart, Denis Noble chronicles the fascinating journey of his research into one of biology's most essential functions — the rhythmic beating of the heart. Written by the founder of mathematical heart modelling, this book traces scientific developments spanning over sixty-five years, from the pioneering 1960 heart rhythm model to the sophisticated integrative models of today. This journey follows the evolution of cardiac electrophysiology through the discovery of potassium and slow channels, analytical modelling, and the development of the electrocardiogram.

Beyond its technical scope, the book describes a profound shift in biological thinking — from a reductionist, gene-centric view of life to a systems-based understanding of living organisms. In doing so, it addresses major philosophical and scientific debates surrounding the foundations of biology, offering a fresh perspective on why genes alone cannot account for the complexity of life. The book will be of great interest to researchers and students specialising in cardiology, as well as philosophers of science and more general readers, presenting a synthesis of rigorous research, theoretical innovation, and wider reflections on a storied career in the biological sciences.

By: Denis Noble (University Of Oxford Uk & Daegu Gyeongbuk Inst Of Science And Technology South Korea)
Imprint: World Scientific Europe Ltd
Country of Publication: United Kingdom
ISBN: 9781800618114
ISBN 10: 1800618115
Pages: 228
Publication Date: 10 November 2025
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Hardback
Publisher's Status: Active