The Mesenteric Organ in Health and Disease

Eli D. Ehrenpreis, John C. Alverdy, Steven D. Wexner

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English

Springer Nature Switzerland AG
04 September 2022

Clinical & internal medicine; Medical imaging; Surgery

Recent discoveries and clarifications of known information about the mesentery have now established that these complex structures function together as an individual organ within the human body. As such, conditions that affect the mesentery can now be grouped within a single area of study and clinical practice.

The various aspects of mesenteric diseases have not been brought together in a single source and this book aims to bring them together for the first time. It will cover general areas such as anatomy, histology and physiology of the mesentery. A description of diagnostic procedures used to evaluate patients with mesenteric disorders will follow. A practical survey with detailed descriptions of medical, surgical, and neoplastic disorders of the mesentery is also be included.

This book is intended to be a guide for clinical practitioners including gastroenterologists, general surgeons, colorectal surgeons, primary care physicians, nurse practitioners and physician assistants who manage patients with mesenteric disorders.

Edited by: Eli D. Ehrenpreis, John C. Alverdy, Steven D. Wexner
Imprint: Springer Nature Switzerland AG
Country of Publication: Switzerland
Edition: 1st ed. 2021
Dimensions: Height: 235mm, Width: 155mm,
Weight: 813g
ISBN: 9783030719654
ISBN 10: 3030719650
Pages: 516
Publication Date: 04 September 2022
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Section 1: General.- Redefining the mesentery as an organ.- Embryology of the mesentery.- General anatomy of the mesentery.- Section II: Anatomy and Physiology.- Vascular Anatomy of the Mesentery.- Introduction to the Physiology of the Mesentery.- Emergence of the human gut microbiota as an influencer in health and disease.- Cellular Anatomy of the Mesentery.- Section III: Diagnostic Procedures.- Radiography of the Mesentery.- Mesenteric biopsy.- Diagnosing mesenteric diseases: Laparoscopy.- Immunologic Function of the MesenteryNeurophysiologic Function of the Mesentery.- Physiology of the Mesenteric Circulation.- Section IV: Role of Mesentery in Systemic Medical Diseases.- The Role of the Mesentery in Metabolic Syndrome and Diabetes Mellitus.- Crohn’s Disease and the Mesentery.- The Role of the Mesentery in Pancreatic diseases.- IgG4-Related Diseases and the Mesentery.- Role of the Mesentery in Systemic Inflammation Response Syndrome (SIRS) and Multiple Organ Dysfunction Syndrome (MODS).- Section V: Medical Disorders of the Mesentery.- Mesenteric Hemorrhage.- Mesenteric Panniculitis.- PPP Syndrome: Pancreatitis, Panniculitis, Polyarthritis.- Mesenteric Adenitis.- Mesenteric Abscess.- Mesenteric Venous Thrombosis.- Mesenteric Arterial Occlusion.- Ischemic Enteropathy (also called Mesenteric Ischemia).- Colonic Ischemia (also known as Ischemic Colitis).- Mesenteric Lymphangioma.- Radiation-Induced Mesenteric Injury.- Drug Induced Mesenteric and Retroperitoneal Diseases.- Section VI: Neoplasms of the Mesentery.- Primary Solid Neoplasms.- Metastatic Diseases of the Mesentery.- Mesenteric Lymphoma.- Castleman Disease with Mesenteric Involvement.- Section VII: Surgical Diseases of the Mesentery.- Mesenteric Resection in Upper Abdominal Surgery.- Mesenteric Considerations in Surgery of the Colon and Rectum.- Mesocolic Resection in Colon Cancer.- Mesenteric Resection in Rectal Cancer.- Mesenteric Resection in Crohn’s disease.- Mesenteric resection inCrohn’s disease.- Section VIII: Surgery for Individual Conditions.- Surgical Management of Intestinal Volvulus.- Embryologic Abnormalities of the Mesentery.- Mesenteric Hernia.- Surgical Management of Bands and Adhesions.- Mesenteric Trauma.- Mesenteric Cysts.- Mesenteric Abscess.- Mesenteric Neoplasms.- Mesenteric Artery Thrombosis and Embolism.- Section IX: Future.- Future Research on the Role of the Mesentery in Health and Disease.

Dr. Ehrenpreis is an internationally recognized expert in the fields of gastroenterology and clinical pharmacology. He is the author/editor of six books including Anal and Rectal Diseases: A Concise Manual and Radiation Therapy for Pelvic Malignancies and its Consequences; both published by Springer. Dr. Ehrenpreis has published more than 100 manuscripts on benign and malignant diseases of the gastrointestinal tract, pharmacokinetics, pharmacovigilance and analysis of big data. He is the Founding Director of the University Chicago (North Shore) Gastroenterology Fellowship training program and is the Founding Director of the Center for the Study of Complex Diseases. Dr. Ehrenpreis is a frequent lecturer at regional and national gastroenterology meetings. He has a particular interest in mesenteric panniculitis, a rare inflammatory disorder of the mesenteric organ and has served on an advisory role related to this condition for the National Organization for Rare Diseases and has been the medical advisor for the International Mesenteric Panniculitis Society for more than 20 years. Dr. Alverdy is a nationally recognized expert in clinical gastrointestinal surgery. He has published more than 100 manuscripts on a variety of subjects including the surgical effects on the intestinal microbiome. Notable contributions to the field include the introduction of several new operations surgical procedures. Dr. Alverdy specializes in minimally invasive pancreatic surgery, bariatric surgery, and surgery for disorders of the foregut including the esophagus and stomach. Steven D. Wexner, MD, PhD (Hon), FACS, FRCS, FRCS(Ed), is the Director of the Digestive Disease Center and Chairman of the Department of Colorectal Surgery since 1993. He previously served as Chief Academic Officer (2007-2012), Chief of Staff (1997-2007), and Chairman of the Division of Research and Education (1996-2007) at Cleveland Clinic Florida. Dr. Wexner haspublished over 550 manuscripts, more than 220 textbook chapters and more than 100 editorial and invited commentaries. He is the editor or co-editor of 26 textbooks or freestanding volumes to date and is a member of 34 editorial boards and a reviewer for an additional 31 journals. He is an active member of 41 learned societies and has held more than 35 appointed or elected offices in these societies. He is an honorary member of the surgical societies of eight other countries and has held over 40 visiting professorships and delivered over 1,270 scientific lectures.