This volume provides an up-to-date collection of protocols describing some of the key methods to investigate the integrated stress response (ISR), a vital evolutionarily conserved mechanism that enables eukaryotic cells to adapt to stress conditions and alter their gene expression programs. The content of the book is split between techniques to analyze mRNA translation regulation and methods to analyze interaction networks and ribonucleoprotein (RNP) granules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Integrated Stress Response: Methods and Protocols serves as an ideal guide to help accelerate research into the complex and fascinating biology of the ISR.
Edited by:
Daniel Matějů, Jeffrey A. Chao Imprint: Humana Country of Publication: United States Edition: 2022 ed. Volume: 2428 Dimensions:
Height: 254mm,
Width: 178mm,
Weight: 976g ISBN:9781071619742 ISBN 10: 1071619748 Series:Methods in Molecular Biology Pages: 404 Publication Date:17 February 2022 Audience:
Adult education
,
Tertiary & Higher Education
Format:Hardback Publisher's Status: Active