For the first time, Drs. Usrey and Sherman, along with a who's who of luminaries in neuroscience research, seek to codify the roles that the cortex and thalamus and their interdependence on each other play for sensation, action, and cognition. The thalamus, in addition, has often been treated as a minor, rather insignificant player in cortical functioning. In the not too distant past, the thalamus was considered a rather boring, machine-like relay of subcortical information to the cortex. Over the past decade, there has been a groundswell of new and renewed interest in the thalamus and thalamocortical interactions, leading to discoveries demonstrating the thalamus's ongoing and essential role in cortical functioning and, likewise, the significance of the cortex for thalamic functioning.
The Cerebral Cortex and Thalamus is a groundbreaking volume bringing together a cohesive account of cortical and thalamic mechanisms for control of behavior with an emphasis on the importance of interactions between the two structures. The book elucidates the research that makes it increasingly clear that the cortex and thalamus are necessary partners for sensory, motor, and cognitive functions. Interactions between thalamus and cortex are not only essential for proper brain function, they are also sensitive to a range of diseases that can have devastating consequences on individuals and society.
An essential text for graduate students, early career investigators, and investigators looking to shift their research focus, The Cerebral Cortex and Thalamus is organized into topical sections covering circuit properties of thalamus and cortex, thalamocortical and corticothalamic motifs, sensory systems, motor systems, interareal cortical communication, cognitive properties, development and plasticity, evolution, computation, and disease.
Contributors Preface Abbreviations Section I: Introduction Chapter 1: Introduction and Overview, W. Martin Usrey and S. Murray Sherman Section II: Thalamic Cell and Circuit Properties Section Introduction: Martha Bickford Chapter 2: Thalamus and Prethalamus Cell Types and Their Interconnections, Martha Bickford Chapter 3: Biophysical Properties of Thalamic Cell Types, Thomas Budde Chapter 4: Heterogeneity of Thalamic Input Landscapes, László Acsády Chapter 5: Synaptic Properties of Thalamic and Prethalamic Inputs, Carmen Varela Section III: Cortical Cell and Circuit Properties Section Introduction: Alex D. Reyes Chapter 6: Anatomical and Physiological Basis for the Flow of Thalamocortical Inputs Across the Layers of the Primary Sensory Cortex, Marcel Oberlaender Chapter 7: Biosphysical Properties of Cortical Excitatory Neurons, Lucy M. Palmer Chapter 8: Functional Roles Cortical Inhibitory Interneurons, Hyeyoung Shin and Hillel Adesnik Chapter 9: Transformation of Receptive Fields Across Laminae, Alex D. Reyes Chapter 10: Neuromodulation in Cortical Circuits, Veronica C. Galvin and Anita A. Disney Section IV: Pathways Between the Thalamus and the Cortex Section Introduction: Francisco Clascá and Sonja Hofer Chapter 11: Thalamic Output Pathways: Global Layout and Nucleus-Level Organization, Francisco Clascá Chapter 12: Thalamic Output Pathways: Single-Cell Organization Level, Francisco Clascá Chapter 13: Thalamortical Synapses, Anthony Holtmaat and Kok-Sin Lee Chapter 14: Structure and Function of Corticothalamic Pathways of Layer 6 Neuron, Allison J. Murphy and Farran Briggs Chapter 15: Corticothalamic Layer 5 Pathways and Synapses, Rebecca A. Mease and Alexander Groh Chapter 16: The Thalamic Reticular Nucleus: Anatomo-Functional Mechanisms and Concept, Didier Pinault Section V: Sensory Systems Section Introduction: Andrew J. King and Judith A. Hirsch Chapter 17: A Comparative Approach to Parallel Geniculocortical Pathways, Samuel G. Solomon Chapter 18: Thalamic Contributions to Visual Cortical Receptive Fields, Ronan O'Shea, Mandi C. Severson, and Nicholar J. Priebe Chapter 19: Corticogeniculate Feedback and Visual Processing, W. Martin Usrey Chapter 20: Visual Processing in the Pulvinar, Angela Y. Fan and James A. Bourne Chapter 21: Auditory Thalamic Nuclei, Cell Types, and Parallel Pathways, Daniel A. Llano Chapter 22: Sensory Representations in the Auditory Cortex and Thalamus, Jennifer F. Linden Chapter 23: The Role of the Thalamus for Human Auditory and Visual Speech Perception, Katharina von Kriegstein and Christa Müller- Axt Chapter 24: Corticothalamic Interactions in the Auditory System, Victoria M. Bajo and Andrea J. King Chapter 25: General Organization and Parallel Pathways in the Somatosensory System, Christina Mo Chapter 26: Duplicated Thalamocortical Input: Lesson sof rhte Somatosensory System, Randy M. Bruno Chapter 27: Layer 6 Corticothalamic Neurons in the Somatosensory System, Solange P. Brown Chapter 28: The Vestibular Thalamus, Kathleen E. Cullen, Jérôme Carriot, and Maurice J. Chacron Chapter 29: Thalamocortical Contribution to Chemical Senses, Emmanuelle Courtiol, Arianna Maffei, and Alfredo Fontanini Chapter 30: Thalamic Contributions to Multisensory Convergence and Processing, Annamaria Barczak, Monica N. O'Connell, and Charles E. Schroeder Section VI: Motor Systems Section Introduction: Adam W. Hantmann and Kevin P. Cross Chapter 31: Thalamic Control of Motor Cortical Synchrony, Abdulraheem Nashef and Yifat Prut Chapter 32: Intrinsic Properties of Neurons in Motor Thalamus and Connected Cortex, Francesco Cavarretta, Taylor Kahl, and Dieter Jaeger Chapter 33: Connectivity of Motor Cortex, Motor Thalamus, and Striatum, Bryan M. Hooks Chapter 34: Models of Thalamocortical Interactions in Motor Control, G. Sean Escola, Kaushik Lakshminarasimhan, and Laureline Logiaco Chapter 35: Thalamocortical Contributions to Neural Dyanmics and Behavior, Jorge Jaramillo and Zengcai V. Guo Chapter 36: Oculomotor Thalamus and Efference Copy, Marc A. Sommer Section VII: Inter-areal Cortical Communication Section Introduction: Alessandra Angelucci Chapter 37: The Evolving Concept of Cortical Hierarchy, Julien Vezoli, Yujie Hou, and Henry Kennedy Chapter 38: Feedforward and Feedback Connections: Functional Connectivity, Synaptic Physiology, and Function, Alessandra Angelucci and Leopoldo Petreanu Chapter 39: Modular Architecture of Layer 1 as a Template for the Organization of the Mouse Distributed Hierarchical Visual Network, Andreas Burkhalter Chapter 40: Mechanisms of Cortico-Cortical Communication, Adam Kohn Chapter 41: Predictive Coding: Forward and Backward Connectivity, Stewart Shipp and Karl Friston Chapter 42: Cortico-Cortical Communication Through the Thalamus: Trans-Thalamic Pathways, Mitra Javadzadeh and Sonja B. Hofer Section VIII: Cognitive Properties Section Introduction: Michael M. Halassa and Sabine Kastner Chapter 43: Memory and the Human Anterior Thalamus, Catherine M. Sweeney-Reed and Robert T. Knight Chapter 44: Memory and the Rodent Anterior Thalamus, Adrien Peyrache and Adrian J. Duszkiewicz Chapter 45: Attention and Thalamocortical Interactions, Sabine Kastner and W. Martin Usrey Chapter 46: The Mediodorsal Thalamus and Decision-Making, Michael M. Halassa and Yuri B. Saalmann Chapter 47: Thalamic Contribution to Cortical Network Functions, Kai Hwang and James M. Shine Chapter 48: Thalamic Bases of Goal-Directed Behaviors, Mathieu Wolff Section IX: Development and Plasticity Section Introduction: Chinfei Chen Chapter 49: Mechanisms Underlying the Refinement of the Retinogeniculate Synapse, Chinfei Chen Chapter 50: Postnatal Development of the Thalamocortical Circuit and Sensory-Driven Cortical Activity, Theofanis Karayannis Chapter 51: Critical Period Plasticity and Development of Binocular Vision, Jianhua Cang and Adema Ribic Chapter 52: Development and Plasticity of Feature Selectivity, Sophie V. Griswold and Stephen D. Van Hooser Chapter 53: Development of Corticothalamic Projections, William Guido Chapter 54: The Connections of the Prefrontal Cortex and Thalamus and Plasticity Within This Circuitry, Anna S. Mitchell Chapter 55: Cross-Modal Plasticity of Cortical and Thalamic Circuits, Lukas Mesik and Hey-Kyoung Lee Section X: Evolution Section Introduction: Leah Krubitzer Chapter 56: The Coevolution of the Neocortex and Dorsal Thalamus in Mammals, Andrew C. Halley and Leah Krubitzer Chapter 57: Evolution of Frontal Cortex and Thalamus in Primates, Mary K.L. Baldwin and Steven P. Wise Chapter 58: Evolution and Development of Thalamocortical Relationships, Zoltan Molnar, Sara Bandiera, and Gavin J. Clowry Chapter 59: Evolution and Elaboration of the Thalamocortical Action Maps, Paul Cisek and Ayuno Nakahashi Section XI: Computational Approaches to Thalamocortical Dynamics, Encoding, and Algorithms Section Introduction: Eric Shea-Brown Chapter 60: Connecting Neural Dynamics and Computation Across Spatial and Temporal Scales, Rebecca A. Mease, Eric Shea- Brown, and Adrienne L. Fairhall Chapter 61: Modeling Thalamocortical Oscillations: Mechanisms and Impact, Ryan Golden and Maxim Bazhenov Chapter 62: Control of Thalamocortical Signaling Through Spike Timing and Synchrony, Garrett B. Stanley Chapter 63: How the LGN Forwards Retinal Information to the Cortex, Friedrich T. Sommer and Judith A. Hirsch Chapter 64: Predictive Coding in Cortical and Corticothalamic Hierarchical Networks, Rajesh P. N. Rao, Linxing Preston Jiang, and Ares Fisher Section XII: Disease and Pathophysiology Section Introduction: Anna S. Mitchell Chapter 65: Corticothalamic Network Abnormalities Underlying Absence Seizures, Nathalie Leresche and Vincenzo Crunelli Chapter 66: Thalamic Dysconnectivity Across the Schizophrenia Illness Course and Psychosis Spectrum, Samantha V. Abram, Caleb M. Spiro, and Judith M. Ford Chapter 67: Thalamus, Thalamocortical Networks, and Non-Motor Symptoms in Parkinson's Disease, John C. Dalrymple- Alford, Tim J. Anderson, and Tracy R. Melzer Chapter 68: Thalamic Changes in Aging and Alzheimer's Disease, Gonzalo Forno and Michael Hornberger Chapter 69: Contribution of Thalamocortical Loops to the Development, Persistence, and Complications of Alcohol Use Disorder, Anne Lise Pitel and Shailendra Segobin Chapter 70: Frontotemporal Dementia, Martina Bocchetta Chapter 71: Visuospatial and Motor Deficits Following Pulvinar Lesions, Melanie Wilke and Igor Kagan Chapter 72: Concluding Thoughts, W. Martin Usrey and S. Murray Sherman Index
W. Martin Usrey, Ph.D., is Professor and Chair of Neurobiology, Physiology and Behavior and Professor of Neurology at UC Davis. His research is focused on understanding the functional properties of neural circuits that serve vision and the relationship between circuit activity, behavior, and perception. He has authored over 70 publications and directed several international courses and conferences on sensory processing and thalamocortical relations. He is the recipient of numerous awards, including the Presidential Early Career Award for Scientists and Engineers. The Usrey laboratory is home to Brainmaps.org, an interactive, high-resolution digital brain atlas and virtual microscope for students, educators, and researchers. He is also editor of sensory systems for the Oxford Research Encyclopedia of Neuroscience. S. Murray Sherman, Ph.D., is Maurice Goldblatt Professor and Chairman in the Department of Neurobiology at the University of Chicago. His books include Exploring the Thalamus, Exploring the Thalamus and its Role in Cortical Function, Functional Connections of Cortical Areas: A New View from the Thalamus, and Exploring Thalamocortical Interactions: Circuitry for Sensation, Action, and Cognition. Dr. Sherman is the author of more than 250 scientific papers, has served on the committees of several scientific organizations and on the editorial boards of multiple journals, and is Editor-in-Chief of the Oxford Research Encyclopedia of Neuroscience. He has held visiting academic positions at universities in the UK and China. The main focus of Dr. Sherman's research is directed towards understanding thalamic functional organization through a variety of interdisciplinary techniques.
