The Biorganic Chemistry of Enzymatic Catalysis

A Tribute to Myron L. Bender (Irving M. Klotz). Myron Lee Bender-An Overview of Scientific Contributions (Fredric M. Menger). Catalytic Activity of 2-Substituted Imidazoles for Hydrolysis of Acyl Ester Derivatives (Masayasu Akiyama). Stoichiometry and Stability of __Cyclodextrin Complexes with Aromatic Substrates in Aqueous Solution (Kenneth A. Conners). An Artificial Enzyme (Valerian T. D'Souza). Mechanisms of Catalysis and Inhibition of ß-Lactamase (Anthony L. Fink). Effect of Ascorbic Acid and Copper on Proteins (Avi Golan-Goldhirsh, David T. Osuga, Andi O. Chen, and John R. Whitaker). Oxalyl Thiolesters, Novel Intermediates in Biological Systems (Gordon Hamilton). Cyclodextrin-Induced Regioselective Cleavages of Ribonucleic Acids (Makoto Komiyama). Esterase-Like Activity and Drug Binding of Human Serum Albumin (Yukihisa Kurono and Ken Ikeda). Identification and Characterization of Reaction Intermediates in the Chemical and Enzymatic Isomerization of ß,_-Unsaturated Ketones to _, ß-Unsaturated Ketones (Ralph M. Pollack). Boronic Acids Catalyze the Hydrolysis of Mandelonitrile (Galla Rao and Manfred Philipp). Activators and Inhibitors of Carboxypeptidase A-Catalyzed Hydrolyses (John F. Sebastian and Jeffery L. Frye). Mediation of Enzyme Catalysis by Intra- and Intersite Changes in Conformational State (Frederick C. Wedler). Effect of Glycosylation on the Enzymatic Activity of Tissue-Type Plasminogen Activators (Arthur J. Wittwer, Susan C. Howard, and Joseph Feder). Viologen Mediators of Desulfovibrio desulfuricans Hydrogenase: Structure-Function Relationships (E. Ziomek, W.G. Martin, and R.E. Williams). Index.