Robert Burton (1577-1640) was born to a family of landed gentry in Leicestershire and matriculated at Oxford at the age of 15. He remained there for the rest of his life, and was eventually appointed librarian of Christ Church College. Inspired by his own struggle with melancholy, Burton began research into the subject, eventually amassing the collection of musings and quotations that would become The Anatomy of Melancholy. First published in 1621, the work was immensely popular, and was expanded and reprinted five times over the course of Burton's life.