Surgical Management of Advanced Pelvic Cancer

List of Contributors viii Preface xiii 1 From Early Pioneers to the PelvEx Collaborative 1 Éanna J. Ryan and P. Ronan O’Connell 2 The Role of the Multidisciplinary Team in the Management of Locally Advanced and Recurrent Rectal Cancer 12 Dennis P. Schaap, Joost Nederend, Harm J.T. Rutten, and Jacobus W.A. Burger 3 Preoperative Assessment of Tumor Anatomy and Surgical Resectability 17 Akash M. Mehta, David Burling, and John T. Jenkins 4 Neoadjuvant Therapy Options for Advanced Rectal Cancer 32 Alexandra Zaborowski, Paul Kelly, and Brian Bird 5 Preoperative Optimization Prior to Exenteration 45 Marta Climent and Miguel Pera 6 Patient Positioning and Surgical Technology 52 Ben Creavin, Michael E. Kelly, and Desmond C. Winter 7 Intraoperative Assessment of Resectability and Operative Strategy 62 Rory Kokelaar, Dean Harris, and Martyn Evans 8 Anterior Pelvic Exenteration 73 Jan W.A. Hagemans, Jan M. van Rees, Joost Rothbarth, Cornelis Verhoef , and Jacobus W.A. Burger 9 Posterior Pelvic Exenteration 85 Werner Hohenberger, Maximilian Brunner, and Susanne Merkel 10 Total Pelvic Exenteration 90 Satish K. Warrier, Andrew C. Lynch, and Alexander G. Heriot 11 Extended Exenterative Resections Involving Bone 97 Timothy Chittleborough, Gordon Beadel, and Frank Frizelle 12 Exenterative Resections Involving Vascular and Pelvic Sidewall Structures 110 Brian K. Bednarski and George J. Chang 13 Extended Exenterative Resections for Recurrent Neoplasm 120 Peter Sagar 14 Pelvic Exenteration in the Setting of Peritoneal Disease 127 Niels Kok, Arend Aalbers, and Geerard Beets 15 Minimally Invasive Pelvic Exenteration 132 Danielle Collins, Christos Kontovounisios, Shahnawaz Rasheed, and Paris Tekkis 16 Stoma Considerations Following Exenteration 138 Gabrielle H. van Ramshorst and Jurriaan B. Tuynman 17 Reconstructive Techniques Following Pelvic Exenteration 149 Dimitrios Patsouras, Alexis Schizas, and Mark George 18 Minimizing Morbidity from Pelvic Exenteration 158 Meara Dean, Alex Colquhoun, Peter Featherstone, Nicola S. Fearnhead, and R. Justin Davies 19 Crisis Management 170 Henrik Kidmose Christensen, Mette Møller Sørensen, and Victor Jilbert Verwaal 20 Quality of Life and Patient-Reported Outcome Measures Following Pelvic Exenteration 177 Daniel Steffens, Cherry Koh, and Michael Solomon 21 Adjuvant Therapy Options after Pelvic Exenteration for Advanced Rectal Cancer 194 Ka On Lam, Jeremy Yip, and Wai Lun Law 22 Adjuvant Therapy Options after Pelvic Exenteration for Gynecological Malignancy 205 Nisha Jagasia 23 Adjuvant Therapy Options for Urological Neoplasms 214 Gregory J. Nason, Clare O’Connell, and Paul K. Hegarty 24 The Role of Re-irradiation for Locally Recurrent Rectal Cancer 223 Johannes H.W. de Wilt and Jacobus W.A. Burger 25 Palliative Pelvic Exenteration 230 Hidde M. Kroon and Tarik Sammour 26 Outcomes of Pelvic Exenteration for Locally Advanced and Recurrent Rectal Cancer 243 Awad M. Jarrar and Scott R. Steele 27 Outcomes Following Exenteration for Urological Neoplasms 255 Frank McDermott, Ian Daniels, Neil Smart, and John McGrath 28 Outcomes Following Exenteration for Gynecological Neoplasms 265 Päivi Kannisto, Fredrik Liedberg, and Marie-Louise Lydrup 29 Mesenchymal and Non-Epithelial Tumors of the Pelvis 283 Eugenia Schwarzkopf and Patrick Boland Index 298