Stem Cells and Revascularization Therapies

Hyunjoon Kong, Andrew J. Putnam, Lawrence B. Schook , Lawrence B Schook

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English

Harper Collins
13 December 2011

Biochemistry; Biotechnology; Materials science

In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. However, both techniques have benefited from multidisciplinary efforts to create biomaterials and other biomedical tools that can improve and control the fate of stem cells, and advance our understanding of them. Stem Cells and Revascularization Therapies focuses on the fundamentals and applied studies in stem cell biology, and provides perspectives associated with the development of revascularization strategies. To help readers understand the multidisciplinary issues associated with this topic, this book has been divided into four sections: Section 1: Explores how to define, isolate, and characterize various stem and progenitor cell populations for neovascularization

Section 2: Summarizes some especially useful model systems and approaches used to regulate angiogenesis, vasculogenesis, and arteriogenesis, and explores their impact on formation of functional vessels in vivo Section 3: Focuses on stem cell homing to sites of injury and inflammation, as well as strategies to exploit this mobilization phenomenon Section 4: Covers stem cell transplantation topics, including recreating features of endogenous stem cell niches to maintain the multipotency of transplanted cells and combinatorial delivery of cells and molecular factors Intended to inspire new contributions to improve the therapeutic efficacy, Stem Cells and Revascularization Therapies outlines emergent findings and challenges regarding the use of stem cells in revascularization therapies. Overcoming the significant hurdles to our understanding of stem cell biology, will enhance their utility in promoting new blood vessel formation.

Edited by: Hyunjoon Kong, Andrew J. Putnam, Lawrence B. Schook, Lawrence B Schook
Imprint: Harper Collins
Country of Publication: United States
Dimensions: Height: 234mm, Width: 156mm, Spine: 23mm
Weight: 800g
ISBN: 9781439803233
ISBN 10: 1439803234
Pages: 500
Publication Date: 13 December 2011
Audience: Professional and scholarly , Undergraduate
Format: Other merchandise
Publisher's Status: Active

Stem Cell Isolation and Purification Technologies. In vitro Stem Cell Culture Technologies. Stem Cell Mobilization Strategies. Stem Cell Transplantation Strategies.