Stem Cells and Cancer in Hepatology

From the Essentials to Application

Yun-Wen Zheng

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English

Academic Press Inc
24 May 2018

Oncology; Hepatology; Biomedical engineering

Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair, the role stem cells play in these processes, and the mechanisms by which liver cancers are initiated and developed. As the field of stem cells and cancer stem cells in hepatology is new and dynamic, thus making it difficult for researchers and clinicians to understand the most relevant historic and novel studies, this volume addresses that challenge.

Edited by: Yun-Wen Zheng
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 151mm,
Weight: 680g
ISBN: 9780128123010
ISBN 10: 012812301X
Pages: 382
Publication Date: 24 May 2018
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

As a stem cell biologist, Dr. Zheng earned his PhD of Medical Science majoring in Physiology/Stem Cell Biology in the University of Tsukuba Graduate School of Medicine, Japan in 2003. From 2003 to present, he has been a team leader for liver and cancer stem cell researches. Dr. Zheng is interested in the identification and isolation of endoderm stem cells as well as liver stem cells in normal and cancer tissues from rodents and human sources; especially for hepatic primordial development and the microenvironment, and drug development, he is trying to generate chimera mouse and rat with humanized livers. Furthermore, for clinical application, he is investigating how to generate the hepatic organoids with cell-cell interactions from the same patient with somatic stem cells from the amnion tissue, umbilical cord and the same source iPS cells. He is also interested in understanding cellular reprogramming and trying cellular therapies, to converse one cell directly into another type in vitro and in vivo.