Over the past decade, the editors have concentrated on stem cell research and the development of stem cell-based models, encompassing the regulation of stem cell stemness and stem cell-based tissue engineering/biosystems/organs-on-chips. Furthermore, their team has extended the application of these models to drug screening, biosensors, and clinical regenerative medicine. Consequently, the editors aim to engage readers interested in the field of stem cell science and technology through the introduction presented in this book.