"Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn's disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.
A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as ""leaky gut."" Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression."
Guest editor:
Susanne M Krug Imprint: Mdpi AG Dimensions:
Height: 244mm,
Width: 170mm,
Spine: 18mm
Weight: 640g ISBN:9783036598642 ISBN 10: 3036598642 Pages: 204 Publication Date:27 December 2023 Audience:
General/trade
,
ELT Advanced
Format:Hardback Publisher's Status: Active