Senescence, Senotherapeutics and Mitochondria

— —

Ufuk Cakatay (Cerrahpasa Faculty of Medicine, Department of Medical Biochemistry, Istanbul University-Cerrahpasa, 34098, Istanbul, Turkey) Mehmet Can Atayik (Hacettepe Faculty of Medicine, Department of General Surgery, Hacettepe University, 06230, Ankara)

Senescence, Senotherapeutics and Mitochondria

Ufuk Cakatay (Cerrahpasa Faculty of Medicine, Department of Medical Biochemistry, Istanbul University-Cerrahpasa, 34098, Istanbul, Turkey), Mehmet Can Atayik (Hacettepe Faculty of Medicine, Department of General Surgery, Hacettepe University, 06230, Ankara)

$301.95

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Academic Press Inc
10 July 2023

Genetics (non-medical); Biochemistry; Molecular biology

Series: Advances in Protein Chemistry and Structural Biology

Senescence, Senotherapeutics and Mitochondria, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more.

Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more.

Volume editor: Ufuk Cakatay (Cerrahpasa Faculty of Medicine Department of Medical Biochemistry Istanbul University-Cerrahpasa 34098 Istanbul Turkey), Mehmet Can Atayik (Hacettepe Faculty of Medicine, Department of General Surgery, Hacettepe University, 06230, Ankara)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 151mm,
Weight: 930g
ISBN: 9780443188862
ISBN 10: 0443188866
Series: Advances in Protein Chemistry and Structural Biology
Pages: 468
Publication Date: 10 July 2023
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

1. Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions Jemima Princilly, Bhavana Veerabhadrappa, Nagashree N. Rao and Madhu Dyavaiah 2. Mitochondria in cell senescence: A Friend or Foe? Qian Chen, Lindon Young, Robert Barsotti 3. The role of mitochondria and mitophagy in cell senescence Tayyab Ali, Fatma Hussain, Haroon Ur Rashid Kayani, Muhammad Naeem, and Fozia Anjum 4. Mitochondria-associated cellular senescence mechanisms: Biochemical and pharmacological perspectives Mehmet Can Atayik and Ufuk Çakatay 5. Changing ROS, NAD and AMP: A path to longevity via mitochondrial therapeutics Oleh Lushchak, Dmytro Gospodaryov, Olha Strilbytska, and Maria Bayliak 6. Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases Siarhei A. Dabravolski 7. Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction Jan O. Nehlin 8. Melatonin as mitochondria-targeted drug Sibel Suzen, Luciano Saso 9. Coenzyme Q-related compounds to maintain healthy mitochondria during aging Guillermo López-Lluch 10. Targeting mitochondrial dysfunction to salvage cellular senescence for managing neurodegeneration Komal Sharma, Joyobrata Sarkar, Anchal Trisal, Rishika Ghosh, Anubhuti Dixit, Abhishek Kumar Singh 11. Targeting the microbiota-mitochondria crosstalk in neurodegeneration with senotherapeutics Jan Homolak 12. Therapeutic targeting of mitochondria–proteostasis axis by antioxidant polysaccharides in neurodegeneration Qiangqiang Wang, Muhammad Zeeshan Adil, Xiaoliang Xie, Shihao Zhao, Ju Zhang, and Zebo Huang 13. Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders Priyanka Sarkar, Ashish Kumar, Partha Sarathi Behera, and Kavitha Thirumurugan

Ufuk Çakatay (May 09, 1965 –) is a Turkish biochemist and biogerontologist. He is a full professor of medical biochemistry at Istanbul-University Cerrahpasa in Istanbul, Turkey. He has a long-standing interest in oxidative protein damage, redox signaling, and biomarkers of proteostasis. Much less is known about the relationship between redox signaling events and senescent cells. However, it has been shown that the number of senescent cells in many tissues increases with age and that senescent cells are found in various age-related diseases. The development of experimental animal models for age-related disorders and the optimization of various bioanalytical techniques for the assessment of redox status in aging tissue are among his major research interests. Professor Çakatay has authored more than 100 publications in several leading journals, including research papers, book chapters, editorials, and invited reviews on free radical biology, aging, diabetes, redox signaling, and senotherapeutics. He has been a guest editor, reviewer, and editorial board member for more than 50 journals. In addition, Professor Çakatay has a keen interest in mentoring medical students and promoting their research careers. He has received several prestigious awards, including the Top Reviewer Award from Elsevier Science Publishing, and was a former member of the Animal Research and Ethics Committee of Istanbul University. Dr. Mehmet Can Atayik is a medical doctor at Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa. He has been working as a scientist and researcher under the mentorship of Professor Ufuk Çakatay since 2017. His research interests are in the fields of aging, age-related disorders, redox biology, oncogenetics, melatonin, mitochondria, surgery, and tissue biochemistry. Doctor Atayik has conducted clinical research, and experimental studies. He has published many scientific papers such as research paper, narrative reviews, and book chapters, and worked as an author, referee, editorial assistant, guest editor, and editor in many prominent publishing houses. He was awarded the Young Investigator Presentation Prize in the VIII. International Congress of Molecular Medicine which was held in Istanbul-Turkey in November 2021.