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RNA Metabolism in Trypanosomes by Albrecht Bindereif at Abbey's Bookshop,
RNA Metabolism in Trypanosomes
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Albrecht Bindereif

RNA Metabolism in Trypanosomes

Albrecht Bindereif

$490.95   $392.41

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English
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
18 July 2014
Medical genetics; Medical parasitology; Genetics (non-medical); Biochemistry; Parasitology (non-medical)
Series: Nucleic Acids and Molecular Biology
Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.
Edited by:  
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Publication:   Germany
Edition:   2012 ed.
Volume:   28
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 15mm
Weight:   433g
ISBN:   9783642433252
ISBN 10:   3642433251
Series:   Nucleic Acids and Molecular Biology
Pages:   274
Publication Date:  
Audience:   College/higher education ,  Further / Higher Education
Format:   Paperback
Publisher's Status:   Active
RNA Polymerases and Transcription Factors of Trypanosomes.- SL RNA biogenesis in kinetoplastids: a long and winding road.- Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and regulation.- mRNA turnover in trypanosomes.- tRNA biogenesis and processing.- rRNA biogenesis in trypanosomes.- RNA Editing in African Trypanosomes – a User’s Guide.- The RNA Interference Pathway in Trypanosoma brucei.- Translation in trypanosomatids.- Mitochondrial translation in trypanosomatids.- RNA-Seq analysis of the transcriptome of Trypanosoma brucei.

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