This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading.
By:
George Milo (Ohio State University), Bruce Casto, Charles Shuler, Charles Shuler Contributions by:
Curtis Harris Imprint: CRC Press Country of Publication: United Kingdom Dimensions:
Height: 234mm,
Width: 156mm,
Weight: 453g ISBN:9781138562745 ISBN 10: 1138562742 Series:CRC Press Revivals Pages: 326 Publication Date:28 January 2019 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active