Reproducibility in Biomedical Research: Epistemological and Statistical Problems

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Erwin B. Montgomery Jr. (Emeritus Professor, Department of Medicine (Neurology), McMaster University, Hamilton, ON, Canada)

Reproducibility in Biomedical Research

Epistemological and Statistical Problems

Erwin B. Montgomery Jr. (Emeritus Professor, Department of Medicine (Neurology), McMaster University, Hamilton, ON, Canada)

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English

Academic Press Inc
18 March 2019

Epidemiology & medical statistics; Cytology; Pharmacology; Medical study & revision guides & reference material; Biophysics

Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries.

By: Erwin B. Montgomery Jr. (Emeritus Professor Department of Medicine (Neurology) McMaster University Hamilton ON Canada)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 151mm,
Weight: 540g
ISBN: 9780128174432
ISBN 10: 0128174439
Pages: 356
Publication Date: 18 March 2019
Audience: Professional and scholarly , Undergraduate
Replaced By: 9780443138294
Format: Paperback
Publisher's Status: Active

1. Introduction2. Validity of Biomedical Science, Reproducibility and Irreproducibility3. The Logic of Certainty versus the Logic of Discovery4. The Logic of Probability and Statistics5. Causation, Process Metaphor, and Reductionism6. Case Studies in Clinical Biomedical Research7. Case Studies in Basic Biomedical Research8. Case Studies in Computational Biomedical Research9. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics10. Epilogue

Dr. Montgomery has been an academic neurologist for over 40 years pursuing teaching, clinical and basic research at major academic medical centers. He has authored over 120 peer reviewed journal articles (available on PubMed) and 8 books on medicine (4 on the subject of Deep Brain Stimulation). The last two have been “Reproducibility in Biomedical Research (Academic Press, 2019) and “The Ethics of Everyday Medicine (Academic Press, 2019).