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English
Academic Press Inc
16 January 2026
Reconstructive Transplantation and Regenerative Surgery: The New Frontier
Edited by:   , , , , , , , , , , , , ,
Imprint:   Academic Press Inc
Country of Publication:   United States
Dimensions:   Height: 276mm,  Width: 216mm, 
Weight:   450g
ISBN:   9780443300844
ISBN 10:   0443300844
Series:   Regenerative and Transplant Medicine
Pages:   288
Publication Date:  
Audience:   Professional and scholarly ,  College/higher education ,  Undergraduate ,  Further / Higher Education
Format:   Hardback
Publisher's Status:   Active
Part I - History of Reconstructive Transplantation 1. Emergence of Reconstructive Transplantation and the Evolution of Regenerative Surgery Part II - Program, Patient and Policy Update 2. Current Status of VCA - A World Update 3. Complications and Mortality in VCA 4. The UNOS - OPTN Mandate for VCA - Emerging Policy and Impact Part III - Decisions and Dilemmas in Reconstructive Transplantation 5. Lower Limb Transplantation - World Experience 6. Complex Combined VCA - Are We Ready? 7. Face Transplantation versus Conventional Reconstruction Part IV - The Cutting Edge of Reconstructive Transplantation 8. Surgical Planning in Face Transplants - From Simulation to Execution 9. The Sensitized VCA Recipient - Regimens and Risks 10. Whole Eye Transplantation Part V - Unique Considerations and Emerging Indications in Reconstructive Transplantation 11. Thyroid Transplantation - Indications and Challenges 12. Tracheal Transplantation - Lessons Learned and Current Progress 13. Penile Transplantation - The Ethics of VCA for Gender Affirmation REGENERATIVE SURGERY Part VI - Graft Targeted Therapies 14. Local Graft Cellular Therapies for Immunomodulation in VCA 15. Biomaterials for Immune Regulation 16. Microneedles for Targeted Immunosuppressive Drug Delivery Part VII - Cellular and Regenerative Therapies in Reconstructive Transplantation 17. Mixed Chimerism in Reconstructive Transplantation 18. Novel Senolytic Therapies - Translational Implications in VCA 19. Exosomal Therapies - Potential and Promise Part VIII - Graft and Patient Monitoring in Reconstructive Transplantation 20. Nanoimaging and Nanotheranostics in Reconstructive Transplantation 21. Biomarker Surrogates for Graft Monitoring 22. Biosensors for Drug Monitoring Part IX - Composite Tissue Graft Manipulation and Engineering 23. Composite Graft Engineering: Concepts and Challenges 24. Composite Graft Decellularization and Recellularization 25. Whole Graft Gene Editing Part X - Tissue Engineering of VCA Components 26. Bioengineered Scaffolds for VCA 27. Engineered Nervous Tissue Constructs for VCA 28. Thymic Engineering for VCA

Dr. Gorantla is a tenured professor of surgery at Wake Forest University School of Medicine and the Wake Forest Institute for Regenerative Medicine. He is the director of the Vascularized Composite Allotransplantation (VCA) Program at Atrium Health Wake Forest Baptist. His research interests include biosensors and biosensing techniques, cellular therapies, nanomedicine, organ transplantations, reconstructive surgeries, regenerative medicine and its applications in transplantation and regenerative, pharmacology. Additionally, he studies the relationship between the immune system and the regenerative, oncogenic and autoimmune processes. Dr. Gorantla was a key member of the team that performed the nation’s first hand transplant at the University of Louisville in 1999. He co-founded the first national society for VCA, the American Society for Reconstructive Transplantation (ASRT). Dr. Gorantla has authored more than 100 scientific papers and 15 book chapters in the field of VCA and is currently co-editing a comprehensive book on the subject of regenerative surgery. Dr. Yalcin Kulahci is a Plastic and Reconstructive Surgeon with specific expertise in Reconstructive Surgery and Microsurgery. He is dual board-certified in Oral and Maxillofacial Surgery and Hand Surgery and was recruited as faculty in 2008 to the Gulhane Military Medical Academy (GMMA) in Istanbul, affiliated with NATO and USUHS. In 2011, Dr. Kulahci was appointed as an Associate Professor at the same institution. In 2012, he became a founding academic staff member for the Department of Hand and Upper Extremity Surgery in Ankara, Turkiye. In 2019, he was recruited to the Wake Forest Institute for Regenerative Medicine following 22 years of honorable service with the Military Health System in Turkey. Dr. Kulahci is currently a faculty member at the Wake Forest School of Medicine and has a comprehensive publication record in clinical reconstructive surgery and microsurgery, with decades of translational research experience in VCA. Dr. Zor is a Plastic and Reconstructive Surgeon with specific expertise in Reconstructive Surgery and Microsurgery. He served as assistant professor of Plastic Surgery and chief combat surgeon in Turkish Armed Forces for over 15 years. Dr. Zor established the first military VCA programs in Turkey and obtained approval for both hand and face transplantation in 2011. Given his field experience in battlefield medicine and expertise in complex reconstruction, tissue regeneration, and hand/face transplantation, he was recruited to Wake Forest Institute for Regenerative Medicine as a faculty in 2017. He participated on several collaborative multi-institutional RTRP and PRMRP awards in the area of reconstructive transplantation and tissue generation. Currently, he's working as Burn Surgery Fellow in Indiana University School of Medicine. My research focus is on immunomodulation, non-invasive VCA monitoring, peripheral and optic nerve regeneration, nanomedicine applications involving transplant and tissue regeneration indications and multimodality imaging strategies for VCA.

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