Prions and Diseases

Wen-Quan Zou, Pierluigi Gambetti

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English

Springer International Publishing AG
03 January 2024

Physiology; Neurology & clinical neurophysiology; Neurosciences; Proteins; Animal physiology

Transmissible spongiform encephalopathies (TSE), known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including the protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains by far the most authoritative views about the past, present, and future of prions and prion diseases. The new second edition covers such important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.

Edited by: Wen-Quan Zou, Pierluigi Gambetti
Imprint: Springer International Publishing AG
Country of Publication: Switzerland
Edition: Second Edition 2023
Dimensions: Height: 235mm, Width: 155mm,
Weight: 1.217kg
ISBN: 9783031205675
ISBN 10: 3031205677
Pages: 793
Publication Date: 03 January 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Wen-Quan Zou, MD, PhD is Professor of Pathology at Case Western University School of Medicine, and he is Associate Director of the National Prion Disease Pathology Surveillance Center. Pierluigi Gambetti, MD, is Professor of Pathology and Neurology at Case Western University School of Medicine.