Principles of Nuclear Magnetic Resonance Microscopy

Callaghan

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English

Clarendon Press
02 December 1993

Microscopy; Electricity, electromagnetism & magnetism; Magnetic resonance

Nuclear magnetic resonance imaging is best known for its spectacular use in medical tomography. However, the method has potential applications in biology, materials science, and chemical physics, some of which have begun to be realized as laboratory NMR spectrometers have been adapted to enable small scale imaging. NMR microscopy has available a rich variety of contrast including molecular specificity and sensitivity to molecular dynamics.

In NMR imaging the signal is acquired in k-space, a dimension which bears a Fourier relationship with the positions of nuclear spins. A dynamic analogue of k-space imaging is the Pulsed Gradient Spin Echo (PGSE) experiment in which the signal is acquired in q-space, conjugate to the distances moved by the spins over a well-defined time interval. q-space microsocpy provides images of the nuclear self-correlation function with a resolution some two orders of magnitude better than is possible in imaging the nuclear density. As well as revealing the spectrum of molecular motion, PGSE NMR can be used to study morphology in porous systems through the influence of motional boundaries.

This book explores principles and common themes underlying these two variants of NMR Microscopy, providing many examples of their use. The methods discussed here are of importance in fundamental biological and physical research, as well as having applications in a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing, and natural product processing.

By: Callaghan
Imprint: Clarendon Press
Country of Publication: United Kingdom
Edition: New edition
Dimensions: Height: 233mm, Width: 157mm, Spine: 28mm
Weight: 1.000kg
ISBN: 9780198539971
ISBN 10: 0198539975
Pages: 510
Publication Date: 02 December 1993
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Principles of imaging; Introductory nuclear magnetic resonance; The influence of magnetic field gradients; High resolution k-space imaging; k-space microscopy in biology and minerals science; The measurement of motion using spin echoes; Structural imaging using q-space; Spatially heterogeneous motion and dynamic NMR microscopy; Elements of the NMR microscope.

Reviews for Principles of Nuclear Magnetic Resonance Microscopy

'The book is well written, the level is appropriate to a graduate student in natural sciences, and it can be recommended to everybody who is interested in an application of NMR microscopy, esepcially of the conventional type (""k-space"" acquisition).' Harry Pfeifer, Zeitschrift für Physikalische Chemie, Bd. 176 (1992) `an excellent introduction to the field which also provides sufficient detail for the expert, so that it can also be used as accompanying material for a course on this subject ... For any scientist, NMR expert or novice who wants to know about the physics of NMR imaging and NMR microsocpy, this is the book to consult. The book is highly recommended for science libraries to acquire and for interested readers to buy.' Berhnard Blümich, Magnetic Resonance in Chemistry, Vol. 33, 322 (1995)