Primary Immunodeficiency Diseases

A Molecular and Cellular Approach

Hans D. Ochs, C. I. Edvard Smith, Jennifer M. Puck

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English

Oxford University Press Inc
19 December 2013

Medical genetics; Hereditary diseases & disorders; Immunology; Paediatric medicine

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options - from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy - this volume will remain an authoritative resource on this increasingly important area.

Edited by: Hans D. Ochs, C. I. Edvard Smith, Jennifer M. Puck
Imprint: Oxford University Press Inc
Country of Publication: United States
Edition: 3rd Revised edition
Dimensions: Height: 287mm, Width: 227mm, Spine: 49mm
Weight: 2.472kg
ISBN: 9780195389838
ISBN 10: 0195389832
Pages: 936
Publication Date: 19 December 2013
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Hans D. Ochs, MD, Dr.med, is Professor of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, WA. C. I. Edvard Smith, MD, PhD, is Professor of Molecular Genetics, Karolinska Institutet, Stockholm, Sweden. Jennifer M. Puck, MD, is Professor of Pediatrics and Medical Director of the Pediatric Clinical Research Center, University of California, San Francisco.