Emma Baker is Professor of Clinical Pharmacology, St. George's, University of London, and Consultant Physician, St. George's Healthcare NHS Trust, London Daniel Burrage is Academic Clinical Fellow, St. George's, University of London, and Specialty Registrar (ST3) in Clinical Pharmacology, General Medicine and Stroke Medicine, St. George's Healthcare NHS Trust, London Dagan Lonsdale is Academic Clinical Fellow, St. George's, University of London, and Specialty Registrar (ST3) in Clinical Pharmacology, General Medicine and Intensive Care Medicine, St. George's Healthcare NHS Trust, London Andrew Hitchings is Clinical Research Fellow, St. George's, University of London, and Specialty Registrar (ST7) in Clinical Pharmacology, General Medicine and Intensive Care Medicine, St. George's Healthcare NHS Trust, London