Rheumatic and autoimmune diseases are often present in women during the childbearing years and as such, correct management of pregnancy throughout its course is of significance to all those affected.
Previously women with systemic rheumatic diseases were counselled against pregnancy as the majority of medications carried potential or perceived teratogenic risk. But in recent years new therapies have emerged that have advanced treatment. Patients have experienced significant improvements in physical function, quality of life, and reduced damage accrual.
As a result, an expanded cadre of health care providers now need to be able to manage pregnancy in women with underlying rheumatic disease, both in acute or chronic settings. Practical Management of the Pregnant Patient with Rheumatic Disease is a quick-access guide of the most up-to-date understanding of the interplay between pregnancy and rheumatic diseases and principles of management before, during and after pregnancy assisting in decision making regarding treatment of women with autoimmune diseases. This collection of 70 cases covers pregnancy counseling, the management of disease flares, thromboembolic disease, the management of patients with end organ disease, advice on medications, obstetric complications, infections and the management of rare diseases in women with rheumatic diseases before and during pregnancy and post-partum. The handbook provides concise recommendations for all providers who may encounter women of child-bearing age including rheumatologists, gynaecologists, paediatricians, primary care providers and health professionals dealing with pre-conceptional and pregnant women with rheumatic diseases.
Edited by:
Karen Schreiber (Copenhagen Lupus and Vasculitis Clinic Copenhagen University Hospital Denmark),
Eliza Chakravarty (Arthritis and Clinical Immunology,
Oklahoma Medical Research Foundation,
USA),
Monika Østensen (Professor of Rheumatology,
Professor of Rheumatology,
Department of Rheumatology,
Sorlandet Hospital,
Kristiansand,
Norway)
Imprint: Oxford University Press
Country of Publication: United Kingdom
Dimensions:
Height: 12mm,
Width: 157mm,
Spine: 234mm
Weight: 39g
ISBN: 9780198845096
ISBN 10: 019884509X
Pages: 240
Publication Date: 11 February 2021
Audience:
Professional and scholarly
,
Undergraduate
Format: Paperback
Publisher's Status: Active
Section One: Counselling 1: Monika Østensen: Important points of pre-pregnancy counselling Section Two: Patients with pre-pregnancy complications 2.1: Andrew James Doyle and Beverley Jane Hunt: Thrombotic Complications in pregnant patients with rheumatic disease 2.2: Roseann O'Doherty and Fionnuala Ní Ainle: Prevention of postpartum venous thromboembolism (VTE) 2.3: Eliza Chakravarty: Pulmonary Arterial Hypertension 2.4: Hannah Blakey and Kate Bramham: Advanced renal disease / renal impairment 2.5: Massimo Radin, Karen Schreiber, and Savino Sciascia: Antibodies as risk factors for adverse maternal and fetal outcomes Section Three: Adjustment of therapy before/during pregnancy and lactation 3.1: Monika Østensen and Ian Giles: Disease modifying drugs, biological drugs and concomitant medications before/during pregnancy and lactation 3.2: Christof Schaefer: Managing a patient exposed to a teratogenic drug at different stages of pregnancy Section Four: Infection during pregnancy 4: Maria Rhona G. Bergantin and Sandra V. Navarra: Infection in a pregnant patient on immunosuppressive treatment Section Five: Organ specific flares during pregnancy 5: Bonnie L. Bermas and Eliza Chakravarty: Managing Organ Specific Flares Section Six: Obstetric complications in women with autoimmune diseases 6: D. Ware Branch: Pregnancy and Obstetric Complications in Women with Autoimmune Diseases Section Seven: Vaccination before or during pregnancy 7: Cara D Varley and Kevin L Winthrop: Vaccination before or during pregnancy Section Eight: Rare diseases in pregnancy 8.1: Karen Schreiber and Monika Ostensen: SLE 8.2: Karen Schreiber and Soeren Jacobsen: Systemic lupus erythematosus and the risk of cardiovascular disease 8.3: Karen Schreiber and Savino Sciascia: 3 Antiphospholipid syndrome 8.4: Megan Clowse and Jon Golenbiewski: Vasculitis in Pregnancy 8.5: Eliza Chakravarty: Systemic sclerosis 8.6: Muhammed Shipa and David Isenberg: Myositis and Pregnancy 8.7: Monika Østensen: Ankylosing spondylitis in pregnancy
Dr Karen Schreiber main clinical and research interests are antiphospholipid syndrome and connective tissue diseases in pregnant women. Dr Schreiber is involved in identifying alternative treatment to improve fetal and maternal pregnancy outcomes in pregnant women with antiphospholipid syndrome. Dr Schreiber is an active member of the British Society for Rheumatology (BSR) working groups publishing clinical guidelines with the overall aim to improve the treatment of patients with rheumatic diseases. Dr. Chakravarty is a rheumatologist and epidemiologist with a longstanding clinical and research interest in understanding the interrelationships between pregnancy and underlying rheumatic diseases. She works to identify and mitigate risk factors for adverse pregnancy outcomes and to optimize medical management of chronic rheumatic diseases during pregnancy and the postpartum period in order to maximize outcomes for both mother and infant. Dr. Østensen is a rheumatologist with a special interest in the interaction between pregnancy and the rheumatic diseases. Her research through many years has focussed on reproduction issues of women and men with rheumatic disease; immunology of pregnancy; antirheumatic drugs during pregnancy and breastfeeding. She has established specialized centers at Rheumatology departments in Norway and in Switzerland that counsel and manage patients who plan a family or are pregnant.
