Poly(ADP-Ribose) Polymerase

Methods and Protocols

Alexei V. Tulin

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Hardback

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English

Springer-Verlag New York Inc.
15 December 2022

Proteins; Enzymology; Cellular biology (cytology)

Series: Methods in Molecular Biology

Summary
Details

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.

Edited by: Alexei V. Tulin
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States [Currently unable to ship to USA: see Shipping Info]
Edition: Third Edition 2023
Volume: 2609
Dimensions: Height: 254mm, Width: 178mm,
Weight: 1.063kg
ISBN: 9781071628904
ISBN 10: 1071628909
Series: Methods in Molecular Biology
Pages: 446
Publication Date: 15 December 2022
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active