This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
Edited by:
Aldo M. Roccaro, Irene M. Ghobrial Imprint: Springer International Publishing AG Country of Publication: Switzerland Edition: Softcover reprint of the original 1st ed. 2016 Volume: 169 Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 19mm
Weight: 563g ISBN:9783319820781 ISBN 10: 3319820788 Series:Cancer Treatment and Research Pages: 361 Publication Date:16 June 2018 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active